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Synergic prooxidant, apoptotic and TRPV1 channel activator effects of alpha-lipoic acid and cisplatin in MCF-7 breast cancer cells

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dc.creator NAZIROĞLU, Mustafa
dc.creator Nur, Gokhan
dc.creator Deveci, Haci Ahmet
dc.date 2016-12-31T21:00:00Z
dc.date.accessioned 2020-10-06T11:01:21Z
dc.date.available 2020-10-06T11:01:21Z
dc.identifier b50c0cb1-39e6-4a32-8604-b4cea8c6ca69
dc.identifier 10.1080/10799893.2017.1369121
dc.identifier https://avesis.sdu.edu.tr/publication/details/b50c0cb1-39e6-4a32-8604-b4cea8c6ca69/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/69929
dc.description Background: Resistance to cisplatin (Cisp) in the treatment of breast cancer is a major obstacle. Alpha-lipoic acid (ALA) has both antioxidant and oxidant properties. ALA has been used on stimulation mechanisms of apoptosis and oxidative stress in the treatment of cancer with a combination of chemotherapeutic agents, although its role on molecular mechanisms in the cancer cells has not been clarified yet. The aim of this study was to evaluate if a combination therapy of ALA with Cisp can alter the effect of this chemotherapy drug in the MCF-7 breast cancer cells.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Synergic prooxidant, apoptotic and TRPV1 channel activator effects of alpha-lipoic acid and cisplatin in MCF-7 breast cancer cells
dc.type info:eu-repo/semantics/article


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