| dc.creator |
TOMRUK, Önder |
|
| dc.creator |
BÜYÜKYAVUZ, Behçet İlker |
|
| dc.creator |
DARICI, Hakan |
|
| dc.creator |
AYLAK, Firdevs |
|
| dc.creator |
DUMAN, Levent |
|
| dc.creator |
GOKCIMEN, Alpaslan |
|
| dc.creator |
CEYHAN, Levent |
|
| dc.creator |
ALTUNTAS, Irfan |
|
| dc.date |
2011-09-30T21:00:00Z |
|
| dc.date.accessioned |
2020-10-06T11:21:49Z |
|
| dc.date.available |
2020-10-06T11:21:49Z |
|
| dc.identifier |
bcbb842d-ca66-47c6-909a-3e57de9c7dc7 |
|
| dc.identifier |
10.1016/j.jpedsurg.2011.03.001 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/bcbb842d-ca66-47c6-909a-3e57de9c7dc7/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/70731 |
|
| dc.description |
Introduction: Accidental ingestion of caustic substances may cause serious problems in children. Approximately 20% of caustic ingestions result in esophageal stricture formation, resulting from excessive collagen synthesis to the extracellular matrix by fibroblasts. Recent studies showed that a single application of 5-fluorouracil (5-FU) is a very effective inhibitor of fibroblast proliferation and differentiation for prolonged periods. Using an experimental model, we investigated the efficacy of single-dose 5-FU on stricture formation after caustic esophageal burn. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
The efficacy of single-dose 5-fluorouracil therapy in experimental caustic esophageal burn |
|
| dc.type |
info:eu-repo/semantics/article |
|