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The effect of cigarette smoking on retinal nerve fiber layer thickness in patients with migraine

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dc.creator TÖK, Özlem
dc.creator Demirci, Seden
dc.creator GÜNEŞ, Alime
dc.creator DEMİRCİ, Serpil
dc.creator TÖK, Levent
dc.creator KUTLUHAN, Süleyman
dc.date 2016-01-01T22:00:00Z
dc.date.accessioned 2020-10-06T11:21:55Z
dc.date.available 2020-10-06T11:21:55Z
dc.identifier bd5bf23b-ff1d-4bd4-b467-acf56a879ec3
dc.identifier 10.3109/15569527.2014.1003935
dc.identifier https://avesis.sdu.edu.tr/publication/details/bd5bf23b-ff1d-4bd4-b467-acf56a879ec3/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/70802
dc.description Context: Migraine is a frequent and disabling chronic neurological condition with complex pathophysiology. Both cigarette smoking and migraine may cause damage to the optic nerve. Objective: The primary objective of this study was to investigate the effect of cigarette smoking on retinal nerve fiber layer (RNFL) thickness in patients with migraine.Materials and methods: Eighty-four consecutive patients diagnosed with migraine (34 smokers and 50 nonsmokers) and 66 age- and gender-matched healthy non-smoker controls were enrolled for this observational cross-sectional study. RNFL thickness was measured using spectral-domain optical coherence tomography (OCT) and then RNFL thickness in patients with migraine who smoke was compared to nonsmoking patients with migraine and healthy subjects.Results: The average, superior, nasal and inferior RNFL thicknesses were significantly thinner in patients with migraine compared to the control group (p<0.001, p=0.02, p<0.001 and p=0.04, respectively). The average and inferior RNFL thicknesses were significantly reduced in smoker patients with migraine compared to the nonsmokers (p=0.011, p=0.045, respectively). Nonsmoker patients with migraine had significantly thinner average and nasal RNFL thicknesses than the control group (p=0.001, p=0.001, respectively).Conclusion: Cigarette smoking may cause significant RNFL thinning in patients with migraine. OCT may be a feasible technique for determination of smoking-induced ocular damage in patients with migraine.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The effect of cigarette smoking on retinal nerve fiber layer thickness in patients with migraine
dc.type info:eu-repo/semantics/article


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