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Low High-Density Lipoprotein Cholesterol Is Characterized by Elevated Oxidative Stress

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dc.creator Karabacak, Mustafa
dc.creator Ozaydin, Mehmet
dc.creator Ersoy, Ismail Hakki
dc.creator Turkdogan, Ahmet Kenan
dc.creator VAROL, Ercan
dc.creator Kahraman, Fatih
dc.date 2014-10-31T22:00:00Z
dc.date.accessioned 2020-10-06T11:24:01Z
dc.date.available 2020-10-06T11:24:01Z
dc.identifier cdd7443f-e6b1-4431-8314-e3a450d11d43
dc.identifier 10.1177/0003319713512173
dc.identifier https://avesis.sdu.edu.tr/publication/details/cdd7443f-e6b1-4431-8314-e3a450d11d43/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/72379
dc.description High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for premature atherosclerosis and cardiovascular disease. Plasma HDL exerts potent antioxidant activity. We evaluated parameters associated with oxidative stress in participants with low HDL-C. This study included 32 patients with low HDL-C (<= 35 mg/dL) and 33 age-and sex-matched control patients with normal HDL-C (> 35 mg/dL). We evaluated clinical and laboratory parameters that are associated with oxidative stress. The oxidative stress index (OSI) levels were significantly higher in the low HDL-C group (3.32 [0.01-13.3] vs 0.74 [0.17-3.55] AU; P <.01) and negatively correlated with HDL-C levels. We suggest that change in OSI and uric acid levels in the study group might indicate increased oxidative status in patients with low HDL-C. This may be associated with increased cardiovascular risk.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Low High-Density Lipoprotein Cholesterol Is Characterized by Elevated Oxidative Stress
dc.type info:eu-repo/semantics/article


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