| dc.creator |
TANYELİ, CİHANGİR |
|
| dc.creator |
Cayir, Merve |
|
| dc.creator |
Demirci, Sema |
|
| dc.creator |
Sezer, Serdar |
|
| dc.date |
2011-06-14T21:00:00Z |
|
| dc.date.accessioned |
2020-10-06T11:24:08Z |
|
| dc.date.available |
2020-10-06T11:24:08Z |
|
| dc.identifier |
cebba67d-eb3b-4f82-8805-45a04b28944e |
|
| dc.identifier |
10.1016/j.tetasy.2011.07.003 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/cebba67d-eb3b-4f82-8805-45a04b28944e/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/72461 |
|
| dc.description |
A ring closing metathesis reaction of dienes and a ring closing enyne metathesis reaction derived from allyl, homoallyl and homopropargyl alcohol backbones are described. 2-Heteroaryl substituted allyl, homoallyl and homopropargyl alcohols have been easily and efficiently resolved through enzymatic resolution with high ee (93-99%) and known stereochemistry. Enantiomerically enriched dienes derived from allyl and homoallyl alcohols afforded the corresponding enantiomerically enriched dihydrofuran and dihydropyran derivatives, respectively, with chemical yields which varied between 72% and 88%. On the other hand, enantiomerically enriched enynes derived from homoallyl and homopropargyl alcohols gave the corresponding optically active dihydropyrans with conjugated diene units with chemical yields between 70% and 80%. A subsequent Diels-Alder reaction of the dihydropyran derivatives with a diene unit with tetracyanoethylene resulted in the formation of a diastereomeric dihydroisochromene ring system as the sole product. (C) 2011 Elsevier Ltd. All rights reserved. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Stereoselective synthesis of optically active dihydrofurans and dihydropyrans via a ring closing metathesis reaction |
|
| dc.type |
info:eu-repo/semantics/article |
|