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Cerebral Venous Sinus Thrombosis as a Rare Complication of Systemic Lupus Erythematosus: Subgroup Analysis of the VENOST Study

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dc.creator Kuosbeci, Ozge Yilmaz
dc.creator Demir, Serkan
dc.creator Colakoglu, Sena
dc.creator Yilmaz, Arda
dc.creator Karahan, Ali Yavuz
dc.creator Duman, Taskin
dc.creator Demirci, Seden
dc.creator Uluduz, Derya
dc.creator KOZAK, HASAN HÜSEYİN
dc.creator Misirli, Cemile Handan
dc.creator Kucukoglu, Hayriye
dc.creator Cinar, Nilgun
dc.creator ÖZTÜRK, ŞEREFNUR
dc.creator SUNGUR, MEHMET ALİ
dc.creator Yayla, Vildan
dc.creator Afsar, Nazire
dc.creator Goksu, Eylem Ozaydin
dc.creator Ince, Birsen
dc.creator Oruc, Serdar
dc.creator Senol, Mehmet Guney
dc.creator Uzuner, Gulnur
dc.creator ÇAĞLAYAN, HALE ZEYNEP BATUR
dc.creator Acikgoz, Mustafa
dc.creator Ozdag, Fatih
dc.creator Ekmekci, Hakan
dc.creator YÜREKLİ, Vedat Ali
dc.creator Genc, Hamit
dc.creator Utku, Uygar
dc.creator ŞAHİN, ŞEVKİ
dc.creator Tokuc, Firdevs Ezgi Ucan
dc.creator UZUNER, Nevzat
dc.creator Bektas, Hesna
dc.creator KABLAN, YÜKSEL
dc.creator Goksel, Basak Karakurum
dc.creator Orken, Dilek Necioglu
dc.creator Aluclu, Ufuk
dc.creator MİDİ, İPEK
dc.creator Tufekci, Ahmet
dc.creator Bakar, Mustafa
dc.creator Tascilar, Nida
dc.creator Goksan, Baki
dc.creator GÖKÇE, MUSTAFA
dc.creator Yalin, Osman Ozgur
dc.creator Kurucu, Hatice
dc.creator Nazliel, Bijen
dc.creator Domac, Fusun Mayda
dc.creator Gunes, Taskin
dc.creator Milanlıoğlu, Aysel
dc.creator Yesilot, Nilufer
dc.creator Aytac, Emrah
dc.creator Cabalar, Murat
dc.date 2019-11-30T21:00:00Z
dc.date.accessioned 2020-10-06T11:24:19Z
dc.date.available 2020-10-06T11:24:19Z
dc.identifier d025d6fb-204b-4fc5-a207-a8873b124e1d
dc.identifier 10.1016/j.jstrokecerebrovasdis.2019.104372
dc.identifier https://avesis.sdu.edu.tr/publication/details/d025d6fb-204b-4fc5-a207-a8873b124e1d/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/72607
dc.description Aim: Systemic lupus erythematosus (SLE) is an unusual risk factor for cerebral venous sinus thrombosis (CVST). As few CVST patients with SLE have been reported, little is known regarding its frequency as an underlying etiology, clinical characteristics, or long-term outcome. We evaluated a large cohort of CVST patients with SLE in a multicenter study of cerebral venous thrombosis, the VENOST study, and their clinical characteristics. Material and Method: Among the 1144 CVST patients in the VENOST cohort, patients diagnosed with SLE were studied. Their demographic and clinical characteristics, etiological risk factors, venous involvement status, and outcomes were recorded. Results: In total, 15 (1.31%) of 1144 CVST patients had SLE. The mean age of these patients was 39.9 +/- 12.1 years and 13 (86.7%) were female. Presenting symptoms included headache (73.3%), visual field defects (40.0%), and altered consciousness (26.7%). The main sinuses involved were the transverse (60.0%), sagittal (40.0%), and sigmoid (20.0%) sinuses. Parenchymal involvement was not seen in 73.3% of the patients. On the modified Rankin scale, 92.9% of the patients scored 0-1 at the 1-month follow-up and 90.9% scored 0-1 at the 1-year follow-up. Conclusions: SLE was found in 1.31% of the CVST patients, most frequently in young women. Headache was the most common symptom and the CVST onset was chronic in the majority of cases. The patient outcomes were favorable. CVST should be suspected in SLE patients, even in those with isolated chronic headache symptoms with or without other neurological findings.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Cerebral Venous Sinus Thrombosis as a Rare Complication of Systemic Lupus Erythematosus: Subgroup Analysis of the VENOST Study
dc.type info:eu-repo/semantics/article


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