| dc.creator |
GÖKÇE, Başak |
|
| dc.creator |
GENÇER, NAHİT |
|
| dc.creator |
ARSLAN, OKTAY |
|
| dc.creator |
Rifati-Nixha, Arleta |
|
| dc.creator |
ARSLAN, MUSTAFA |
|
| dc.creator |
Cikrikici, Kubra |
|
| dc.date |
2019-05-31T21:00:00Z |
|
| dc.date.accessioned |
2020-10-06T11:37:22Z |
|
| dc.date.available |
2020-10-06T11:37:22Z |
|
| dc.identifier |
e20e46ec-f45a-4b6d-ac62-019aeedbab2d |
|
| dc.identifier |
10.1002/jbt.22306 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/e20e46ec-f45a-4b6d-ac62-019aeedbab2d/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/74360 |
|
| dc.description |
The synthesis of carbazole containing pyridopyrimidine-substituted sulfonamide derivatives (3a-i) and their inhibitory effects on human carbonic anhydrase (hCA) I and II were studied. Spectral data and elemental analysis confirmed the structures of the compounds synthesized. The results show that all the synthesized compounds inhibited the CA I and II activities. Among them, 3a was found to be the most active (K-i: 14 mu M) for hCA I and 3f (K-i: 126 mu M) for hCA II. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Synthesis of carbazole bearing pyridopyrimidine-substituted sulfonamide derivatives and studies their carbonic anhydrase enzyme activity |
|
| dc.type |
info:eu-repo/semantics/article |
|