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Effects of a specially pulsed electric field on an animal model of wound healing

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dc.creator ÇÖMLEKÇİ, Selçuk
dc.creator ŞENOL, Nurgül
dc.creator ÇINAR, Kenan
dc.date 2009-08-31T21:00:00Z
dc.date.accessioned 2020-10-06T12:02:59Z
dc.date.available 2020-10-06T12:02:59Z
dc.identifier f949e8bd-de5c-4e5e-a554-bc1db07d8e73
dc.identifier 10.1007/s10103-008-0631-6
dc.identifier https://avesis.sdu.edu.tr/publication/details/f949e8bd-de5c-4e5e-a554-bc1db07d8e73/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/76684
dc.description The possible beneficial effects of a specially pulsed electric field (PEF) on wound healing were investigated in this study. We made a pair of triangular, full-thickness, dorsal incisions in the skin of 32 healthy male mice (one control group and three exposure groups). The treatment groups were kept between parallel plates in a partially insulated exposed environment. Group I was exposed to an electric field intensity of 10 kV/m, group II was exposed to 1.9 kV/m, and group III was exposed to 0.9 kV/m. PEFs were applied to the subjects for 20-22 h and 8 consecutive days. We determined the differences in wound recovery between the groups based on the following parameters: collagen fiber density, inflammatory infiltration density, capillary proliferation, and existence of exudates. We found that a 0.9 kV/m-1.9 kV/m chopped direct current (DC) electric field with a 30 A mu s repetition time favorably affected collagen synthesis and wound recovery. Despite the intensity of 0.9-1.9 kV/m, PEF accelerated healing, but 10 kV/m decelerated this recovery process.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Effects of a specially pulsed electric field on an animal model of wound healing
dc.type info:eu-repo/semantics/article


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