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Serum beta 2-microglobulin reflects disease activity in Behcet's disease

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dc.creator Kaftan, O
dc.creator Bavbek, N
dc.creator Aygunduz, M
dc.creator Kosar, A
dc.creator Kirazli, S
dc.creator Ozturk, M
dc.date 2002-05-01T00:00:00Z
dc.date.accessioned 2021-12-03T11:14:20Z
dc.date.available 2021-12-03T11:14:20Z
dc.identifier 01329d14-4c57-4088-a324-53b78ddb3e18
dc.identifier 10.1007/s00296-002-0180-4
dc.identifier https://avesis.sdu.edu.tr/publication/details/01329d14-4c57-4088-a324-53b78ddb3e18/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/89645
dc.description Behcet's disease (BD) is a systemic remitting vasculitis characterized by orogenital ulceration and uveitis. The disease is not associated with specific laboratory abnormalities. Hence, the activity of BD is generally assessed by clinical findings and - to some extent by nonspecific markers of inflammation. This study was performed to investigate the relative efficiency of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), serumamyloid A protein (SAA), and beta 2-microglobulin (beta 2-m) levels as markers of disease activity in patients with BD. The study population consisted of 20 patients with active BD. 23 patients with inactive BD, and 27 healthy adults serving as the control group. Serum beta 2-m, SAA. ESR, and CRP levels of patients with BD were found to be significantly higher than those in the healthy control group. They were also higher in patients with active disease than in those in remission and controls. The levels of SAA. ESR, and CRP in inactive patients were also significantly hi her than the controls. No statistically significant difference was noted between beta 2-m levels of patients with inactive BD and healthy controls. Serum beta 2-m levels can beregarded as a more discriminative marker of activation in BD. The high diagnostic value of SAA levels indicate that it can also be accepted as a marker of disease activity in BD.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Serum beta 2-microglobulin reflects disease activity in Behcet's disease
dc.type info:eu-repo/semantics/article


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