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Vascular wall damage in rats induced by organophosphorus insecticide methidathion

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dc.creator Ibrisim, E
dc.creator Kutsal, A
dc.creator Cora, A
dc.creator Candir, O
dc.creator Karahan, N
dc.creator Altuntas, I
dc.creator Yildirim, B
dc.creator Delibas, N
dc.creator Yavuz, T
dc.date 2005-01-15T01:00:00Z
dc.date.accessioned 2021-12-03T11:14:36Z
dc.date.available 2021-12-03T11:14:36Z
dc.identifier 05dc3ae2-85b1-4a0e-b37a-13f65f0cd36f
dc.identifier 10.1016/j.toxlet.2004.08.012
dc.identifier https://avesis.sdu.edu.tr/publication/details/05dc3ae2-85b1-4a0e-b37a-13f65f0cd36f/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/89746
dc.description We have examined the effect of subchronic methidathion (MD) administration on vascular wall damage. The experimental groups were: control group and rats treated with 5 mg/kg MD. The MD group was given MD by gavage for 5 days a week for 4 weeks at a dose level of 5 mg/kg per day by using corn oil as the vehicle. The levels of malondialdehyde (MDA) were determined in the vascular tissue. Histopathological examination was examined in-the thoracic aortic tissue. The levels of MDA were increased in the MD group compared with the control group (P <0.01). In the MD group, subchronic MD administration led to the irregulation, prominent breaks and fragmentation of the elastic fibers were located in the media of aortic wall.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Vascular wall damage in rats induced by organophosphorus insecticide methidathion
dc.type info:eu-repo/semantics/article


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