| dc.creator |
Dogan, A |
|
| dc.creator |
Altinbas, A |
|
| dc.creator |
Gedikli, O |
|
| dc.creator |
Ergene, O |
|
| dc.creator |
Tunc, B |
|
| dc.creator |
Nazli, C |
|
| dc.creator |
Ozaydin, M |
|
| dc.date |
2003-12-01T01:00:00Z |
|
| dc.date.accessioned |
2021-12-03T11:14:48Z |
|
| dc.date.available |
2021-12-03T11:14:48Z |
|
| dc.identifier |
095b05b9-6029-49dd-a42b-2a9c8a50c512 |
|
| dc.identifier |
10.1023/b:caim.0000004339.30038.8d |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/095b05b9-6029-49dd-a42b-2a9c8a50c512/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/89822 |
|
| dc.description |
Objective: Since the role of fibrinolytic activity is unclear in coronary artery ectasia, we investigated the entire fibrinolytic activity by a new test, global fibrinolytic capacity (GFC) in the ectasia patients. Methods and results: Thirty-four ectasia patients (18 male, mean age: 58 +/- 8 years) presenting with acute coronary syndrome and 25 controls (14 male, mean age: 56 +/- 9 years) with normal coronary artery were evaluated. GFC, D-dimer and other hemostatic factors were assessed. Clinical characteristics were comparable in both groups. Serum GFC (4.6 +/- 2.1 vs. 3.1 +/- 2.1 mug/ml, p = 0.03) and D-dimer levels (0.69 +/- 0.42 vs. 0.41 +/- 0.38 ng/ml, p = 0.02, respectively) were significantly higher in ectasia patients than in controls. They were also higher in subgroup of patients with myocardial infarction (four patients) compared with other ectasia patients and controls (p = 0.04, 0.01, respectively). Other hemostatic factors were not different in both groups. GFC was correlated with D-dimer (r = 0.76, p = 0.01). Conclusion: Our results suggest that fibrinolytic system activation may develop in ectasia patients with acute coronary syndrome. It can be induced by thrombus formation in ectatic segment of coronary artery. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Evaluation of overall fibrinolytic activity in patients with coronary artery ectasia: Global fibrinolytic capacity |
|
| dc.type |
info:eu-repo/semantics/article |
|