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A dilemma for women: having many children risks deterioration of diastolic functions

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dc.creator Ozgeyik, Mehmet
dc.creator ASTARCIOĞLU, MEHMET ALİ
dc.creator KUYUMCU, Mevlüt Serdar
dc.creator Yildirim, Ozge Turgay
dc.date 2021-06-01T00:00:00Z
dc.date.accessioned 2021-12-03T11:15:12Z
dc.date.available 2021-12-03T11:15:12Z
dc.identifier 1055907c-b33e-4b75-a8ed-e750a22fe1fa
dc.identifier 10.31083/j.ceog.2021.03.2348
dc.identifier https://avesis.sdu.edu.tr/publication/details/1055907c-b33e-4b75-a8ed-e750a22fe1fa/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/89986
dc.description Background: Echocardiography is the most widely used diagnostic tool for detecting changes in cardiac function. Pregnancy is a dynamic process that affects the cardiovascular system and recent studies have shown that increased parity may cause irreversible changes in the cardiovascular system. In this study, we aimed to evaluate echocardiographic changes in women, especially grand multiparous (6 to 9 parities) and great grand multiparous (more than 9 parities) women, after all their pregnancies had finished. Methods: This was a cross-sectional study and contained 195 female patients. Women with one delivery were defined as primiparous (PP), 2 to 5 deliveries were defined as multiparous (MP), 6 to 9 deliveries were defined as grand multiparous (GMP) and more than 9 deliveries were defined as great grand multiparous (GGMP). Results: The mean age at cardiac evaluation was 50.6 +/- 16.3 and mean parity was 6.5 +/- 4.2. Diastolic dysfunction was grouped as grade 1-3 and this was determined according to the E/e' ratio. Spearman correlation analysis showed that diastolic dysfunction had positive correlations with parity, age, hypertension, and diabetes mellitus. Receiver-operating curve (ROC) analysis showed that the best cut-off value of the parity number for predicting left ventricular diastolic dysfunction was 6.5, with 66.3% sensitivity and 66.7% specificity. Discussion: In the present study, we showed that diastolic dysfunction significantly increased as the number of pregnancies increased. Additionally, the cut-off value of parity for diastolic dysfunction was 6.5 which is higher than other studies.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title A dilemma for women: having many children risks deterioration of diastolic functions
dc.type info:eu-repo/semantics/article


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