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Impact of COVID-19 outbreak on patients with ST-segment elevation myocardial infarction (STEMI) in Turkey: results from TURSER study (TURKISH St-segment elevation myocardial infarction registry)

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dc.creator Altindag, Rojhad
dc.creator Kilicaslan, Baris
dc.creator Yildirim, Tarik
dc.creator Aktas, Zihni
dc.creator KARABACAK, Mustafa
dc.creator Oz, Ahmet
dc.creator MURAT, SELDA
dc.creator Arik, Baran
dc.creator Gul, Sefa
dc.creator Ergene, Asim Oktay
dc.creator Kiris, Tuncay
dc.creator AVCI, EYÜP
dc.creator Ekin, Tuba
dc.creator Akgun, Didar Elif
dc.creator Tiryaki, Mucahit
dc.creator Yidirim, Arafat
dc.creator Hazir, Kutluhan
dc.creator Murat, Bektas
dc.creator Yeni, Mehtap
dc.creator Guzel, Tuncay
dc.date 2022-02-01T00:00:00Z
dc.identifier 229ab696-3f42-4699-9c2f-c8871ea6db45
dc.identifier 10.1007/s11239-021-02487-3
dc.identifier https://avesis.sdu.edu.tr/publication/details/229ab696-3f42-4699-9c2f-c8871ea6db45/oai
dc.description Objective We aimed to investigate both the impact of COVID-19 pandemic on ST-segment elevation myocardial infarction (STEMI) admission, and demographic, angiographic, procedural characteristics, and in-hospital clinical outcomes of patients with COVID-19 positive STEMI in Turkey. Methods This was a multi-center and cross-sectional observational study. The study population included 1788 STEMI patients from 15 centers in Turkey. The patients were divided into two groups: COVID-19 era (March 11st-May 15st, 2020; n = 733) or pre- COVID-19 era group (March 11st-May 15st, 2019; n = 1055). Also, the patients in COVID-19 era were grouped as COVID-19 positive (n = 65) or negative (n = 668). Results There was a 30.5% drop in STEMI admission during COVID-19 era in comparison to pre-COVID-19 era. The patients admitted to the medical centers during COVID-19 era had a longer symptom-to-first medical contact time [120 (75-240) vs. 100 (60-180) minutes, p < 0.001]. COVID-19 positive STEMI patients had higher thrombus grade and lower left ventricular ejection fraction compared to COVID-19 negative patients. COVID-19 positive patients had higher mortality (28% vs. 6%, p < 0.001) and cardiogenic shock (20% vs. 7%, p < 0.001) rates compared with those without COVID-19. Matching based on propensity scores showed higher mortality and high thrombus grade in STEMI patients who were infected by SARS-COV-2 (each p < 0.05). Conclusions We detected significantly lower STEMI hospitalization rates and significant delay in duration of symptom onset to first medical contact in the context of Turkey during the COVID-19 outbreak. Moreover, high thrombus grade and mortality were more common in COVID-19 positive STEMI patients.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Impact of COVID-19 outbreak on patients with ST-segment elevation myocardial infarction (STEMI) in Turkey: results from TURSER study (TURKISH St-segment elevation myocardial infarction registry)
dc.type info:eu-repo/semantics/article


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