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The Impacts of Helicobacter Pylori Antigen Positivity on Ankylosing Spondylitis

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dc.creator Yener, Mahmut
dc.creator Ergun, Ayse Gul
dc.creator Canak, Sultan
dc.creator Aynali, Ayse
dc.creator Inal, Esra Erkol
dc.creator KAYA, SELÇUK
dc.creator Inal, Salih
dc.date 2016-05-01T00:00:00Z
dc.date.accessioned 2021-12-03T11:20:38Z
dc.date.available 2021-12-03T11:20:38Z
dc.identifier 4001e037-c304-4d8c-b16c-fc26553eba89
dc.identifier 10.4328/jcam.2767
dc.identifier https://avesis.sdu.edu.tr/publication/details/4001e037-c304-4d8c-b16c-fc26553eba89/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/91105
dc.description Aim: We aimed to clarify the impacts of H. pylori infection on disease activity and clinical findings of AS. Material and Method: Forty-eight patients with AS were included in this study. The demographic data including age, sex, durations of the disease and medication of the patients were recorded. The laboratory analysis comprised Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and H. pylori antigen determination in gaita. The disease activity, functional disability and clinical status were assessed using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), The Bath Ankylosing Spondylitis Functional index (BASFI) and The Bath Ankylosing Spondylitis Metrology Index (BASMI) respectively. We divided patients according to H. pylori antigen positivity in gaita as H. pylori positive and negative patients. Results: The mean age of patients was 41.9+11.8. CRP levels were slightly but not significantly higher in patients with positive H. pylori antigen compared to those in patients without H. pylori antigen in gaita (p=0.08). There was no significant difference in terms of ESR levels, BASDAI, BASFI and BASMI scores in patients with positive H. pylori antigen compared to those in patients with negative H. pylori antigen in gaita (p-values were >0.05 for all). In regression model BASDAI score was found to have no relationship with H. pylori antigen positivity, ESR and CRP levels (p-values were > 0.05 for all). Discussion: H. pylori seemed to have probable impacts on the disease activity of AS. Studies with greater patient population and longer follow-up periods are warranted to enlighten this issue.
dc.language eng
dc.rights info:eu-repo/semantics/openAccess
dc.title The Impacts of Helicobacter Pylori Antigen Positivity on Ankylosing Spondylitis
dc.type info:eu-repo/semantics/article


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