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Effectiveness of oxybutynin hydrochloride in the treatment of enuresis nocturna - A clinical and urodynamic study

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dc.creator Dincel, C
dc.creator Kosar, A
dc.creator Arikan, N
dc.date 1999-04-01T00:00:00Z
dc.date.accessioned 2021-12-03T11:29:18Z
dc.date.available 2021-12-03T11:29:18Z
dc.identifier 5cef70af-9929-4731-953b-39532e018f2b
dc.identifier 10.1080/003655999750016096
dc.identifier https://avesis.sdu.edu.tr/publication/details/5cef70af-9929-4731-953b-39532e018f2b/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/92096
dc.description Objective: To find the efficacy and optimal dosage of oxybutynin HCl in a group of enuretic children, who were non-responsive to imipramine. Material and Methods: Thirty-six patients with enuresis who were non-responsive to imipramine were urodynamically assessed and subsequently treated with oxybutynin hydrochloride (HCl). Patients with inadequate bladder storage function (IBSF) were started on 10-mg daily oxybutynin HCl for one month. If the initial treatment was found to be inadequate, the dose was increased to 15 mg daily. The dose in patients who were non-responsive to 15-mg daily dose was increased to 20-mg daily dose. Patients who were normal urodynamically were treated with a dose of 15 mg daily for one month. Results: Before the treatment, 17 patients had IBSF (47.2%). The majority of the patients (88.2%) with IBSF were responsive to the 15-mg daily oxybutynin HCl. The treatment in patients with normal bladder function was generally unsuccessful. Conclusions: Oxybutynin HCl in sufficient dosages seems to be effective in the treatment of enuretic patients with IBSF.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Effectiveness of oxybutynin hydrochloride in the treatment of enuresis nocturna - A clinical and urodynamic study
dc.type info:eu-repo/semantics/article


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