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Chemometric Determination of Coloring Agents Used in Drugs

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dc.creator Ertokuş, Güzide
dc.creator Metin, Hande
dc.date 2021-05-01T00:00:00Z
dc.date.accessioned 2021-12-03T11:29:36Z
dc.date.available 2021-12-03T11:29:36Z
dc.identifier 625e2584-242c-4459-85c7-3d0a5c25d0cb
dc.identifier 10.23880/macij-16000168
dc.identifier https://avesis.sdu.edu.tr/publication/details/625e2584-242c-4459-85c7-3d0a5c25d0cb/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/92212
dc.description <p>The chemometric determination of titanium dioxide and indigotin in drug by the principal component regression (PCR)was performed with spectrophotometric method. Chemometric methods are used in spectral data analysis of mixturescontaining two or more compounds. With chemometric techniques, even complex systems are allowed to be analyzedspectrophotometrically as is without any pre-separation process. In this study, an alternative, lower cost and more reliablemethod has been developed in chemometric analysis of the colorants used in drugs. The investigation of the accuracy andrepeatability of the two methods resulted in high recovery rates and lower standard deviation values. Achieving high recoveryrates and lower standard deviation values, this study encouraged us to proceed further in drug analysis. The proposed methodsare highly sensitive and precise as they have been successfully applied to quantify active substances in pharmaceutical samples.&nbsp;<br></p>
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Chemometric Determination of Coloring Agents Used in Drugs
dc.type info:eu-repo/semantics/article


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