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Salvia nemorosa L.: A novel source of bioactive agents with functional connections

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dc.creator Zengin, Gokhan
dc.creator Bahadori, Shahram
dc.creator Abbas-Mohammadi, Mandi
dc.creator Sarikurkcu, Cengiz
dc.creator Dinparast, Leila
dc.creator Asghari, Behvar
dc.creator Bahadori, Mir Babak
dc.date 2017-01-01T00:00:00Z
dc.date.accessioned 2021-12-03T11:30:17Z
dc.date.available 2021-12-03T11:30:17Z
dc.identifier 6f2dfb3e-fdce-485f-bc4b-7027ef3e362c
dc.identifier 10.1016/j.lwt.2016.08.048
dc.identifier https://avesis.sdu.edu.tr/publication/details/6f2dfb3e-fdce-485f-bc4b-7027ef3e362c/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/92471
dc.description Salvia species are used as food and medicinal plants all around the world. In this study, chemical composition and antimicrobial, toxicity, antioxidant, and enzyme inhibitory activity of Salvia nemorosa were evaluated. Phenolic components were characterized by the HPLC-DAD and 11 components were identified, in which rosmarinic acid was detected as the major compound (7584 mu g/g extract). Sixteen volatile components were determined in both leaves and flowers essential oils. Oxygenated sesquiterpenes were the major components. Methanolic extract showed the highest total phenolic and flavonoid contents (294 mg GAE/g and 117 mg QE/g extract, respectively) and the strongest DPPH radical scavenging activity (IC50: 82 mu g/mL). Plant samples showed moderate to high aldehyde oxidase, xanthine oxidase, acetylcholinesterase, and alpha-glucosidase inhibitory activity and moderate cytotoxicity. Also, EOs exhibited great antimicrobial potential (IZ: 8.8-33.7 mm). Our findings indicated that S. nemorosa may be useful for novel applications in functional food and pharmaceutical industries. (C) 2016 Elsevier Ltd. All rights reserved.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Salvia nemorosa L.: A novel source of bioactive agents with functional connections
dc.type info:eu-repo/semantics/article


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