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The effect of replacement fluids and normovolaemic haemodilution on the survival of dorsal skin flaps in rats

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dc.creator Tunc, B
dc.creator Delibas, N
dc.creator Dogru, H
dc.creator Eroglu, E
dc.creator Tuz, M
dc.creator Uygur, K
dc.date 2004-02-01T01:00:00Z
dc.date.accessioned 2021-12-03T11:30:49Z
dc.date.available 2021-12-03T11:30:49Z
dc.identifier 782d3168-2d4f-4641-a15f-0514c605c08b
dc.identifier 10.1111/j.1365-2273.2004.00787.x
dc.identifier https://avesis.sdu.edu.tr/publication/details/782d3168-2d4f-4641-a15f-0514c605c08b/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/92798
dc.description The objective of this study is to investigate the effect of normovolaemic haemodilution (anaemia), haemoglobin level and replacement fluids on the survival of local flaps in rats. Fifty male Wistar rats were divided into four study groups and one control group (10 rats for each). In the study groups, 20% or 30% of blood was withdrawn and replaced by either Gelofusine((R)) or saline (0.9%). Single 1.5 cm x 3 cm cranially based dorsal random skin flaps consisting of skin and panniculus carnosus were elevated in all rats. No difference was determined between the control and 20% exsanguinated groups regarding flap survival area. There was a statistically significant difference between the flap survival areas of 20% exsanguinated groups and 30% exsanguinated groups. If the blood loss exceeds 30% of total volume and/or haemoglobin (Hb) level is lower than 10.72 g/dL, the risk of flap necrosis increases significantly.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The effect of replacement fluids and normovolaemic haemodilution on the survival of dorsal skin flaps in rats
dc.type info:eu-repo/semantics/article


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