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Free insulin-like growth factor-1 levels in bladder growth following spinal cord injury experimentally

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dc.creator Hoscan, MB
dc.creator Kilic, S
dc.creator Soyupek, S
dc.creator Kutluhan, S
dc.creator Uysal, E
dc.creator Serel, TA
dc.date 2005-01-01T01:00:00Z
dc.date.accessioned 2021-12-03T11:31:32Z
dc.date.available 2021-12-03T11:31:32Z
dc.identifier 84dcee3a-e8fc-4c41-b17c-179dc601f7ea
dc.identifier 10.1159/000087808
dc.identifier https://avesis.sdu.edu.tr/publication/details/84dcee3a-e8fc-4c41-b17c-179dc601f7ea/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/93084
dc.description Introduction: To determine the levels of spinal cord injury (SCI) on free insulin- like growth factor-1 ( IGF-1) content in the bladder and the possible role of free IGF-1 in growth in hypertrophic bladders in an experimental model. Materials and Methods: The contents of free IGF1 and protein in paraplegic and non- paraplegic rats which was induced experimentally by SCI were measured. The wet weights of the bladders were also determined. The results gained were compared. Results: The mean bladder free IGF- 1 level in paraplegic rats was significantly higher than the corresponding bladder free IGF-1 level in sham-operated bladder (p < 0.05). Mean wet weight bladder in paraplegic rats was signifi cantly higher than the sham-operated rats (p < 0.05). Paraplegic bladder had a signifi cantly higher mean protein content than the sham-operated bladder (p < 0.05). Serum free IGF-1 levels in the two groups were not different. Conclusion: Our pilot study reveals that free IGF-1 may be effective in SCI. Copyright (c) 2005 S. Karger AG, Basel.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Free insulin-like growth factor-1 levels in bladder growth following spinal cord injury experimentally
dc.type info:eu-repo/semantics/article


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