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Long term effects of mild severity COVID-19 on right ventricular functions

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dc.creator BAĞCI, Ali
dc.creator Sener, Yusuf Ziya
dc.creator Kaya, Ahmet
dc.creator Yenercag, Feyza Nur Topcu
dc.creator Akkaya, Fatih
dc.date 2021-07-01T00:00:00Z
dc.date.accessioned 2021-12-03T11:32:07Z
dc.date.available 2021-12-03T11:32:07Z
dc.identifier 8fee95b5-42d9-4727-a89b-e65d631dd108
dc.identifier 10.1007/s10554-021-02340-x
dc.identifier https://avesis.sdu.edu.tr/publication/details/8fee95b5-42d9-4727-a89b-e65d631dd108/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/93305
dc.description Coronavirus disease 2019 (COVID-19) is a newly recognized infectious disease that has spread rapidly. COVID-19 has been associated with a number of cardiovascular involvements, including ventricular functions. The aim of our study was to evaluate the right ventricular functions of mild severity COVID-19 patients 3 months after, and compare them to the right ventricular functions of healthy volunteers. For this single-center study, data from 105 patients who were treated for mild severity COVID-19 between September 15, 2020 and December 31, 2020 were collected. 105 age and sex matched healthy subjects were included in the study. Right ventricular (RV) functions were evaluated using conventional two-dimensional (2D) echocardiography and 2D speckle-tracking echocardiography (STE) for all patients. 2D-E parameters indicating RV functions were compared between the two groups. RV diamaters, systolic pulmonary artery pressure (sPAP) and RV myocardial performance index (RV MPI) were significantly higher in the COVID-19 patients compared to control group (p < 0.05). Tricuspid annular plane systolic motion (TAPSE), right ventricular fractional area change (RVFAC) and RV S' were significantly lower in the COVID-19 group compared to control group (p < 0.05). RV global longitudinal strain (RV-GLS) (- 19.6 +/- 5.2 vs. - 15.1 +/- 3.4, p < 0.001) and RV free wall longitudinal strain RV-FWLS (- 19.6 +/- 5.2 vs. - 17.2 +/- 4.4, p < 0.001) values were significantly lower in the COVID-19 group than the control group. There was a significant negative correlation between RV-FWLS, RV-GLS and C-reactive protein (CRP), neutrophil to lymphocyte ratio (NLR), d-dimer, ferritin, platelet to lymphocyte ratio (PLR) in patients with mild severity COVID-19. This results suggested that RV-GLS and RV-FWLS decreased in the long term (third month) follow-up of patients treated for mild severity COVID-19 disease. Subclinical RV dysfunction may be observed in patients after mild severity COVID-19.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Long term effects of mild severity COVID-19 on right ventricular functions
dc.type info:eu-repo/semantics/article


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