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The Importance of Melatonin and Mitochondria Interaction in Mood Disorders and Schizophrenia: A Current Assessment

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dc.creator Espino, Javier
dc.creator Demirci, Kadir
dc.creator Uguz, Abdulhadi Cihangir
dc.date 2016-01-01T01:00:00Z
dc.date.accessioned 2021-12-03T11:32:32Z
dc.date.available 2021-12-03T11:32:32Z
dc.identifier 97642b8e-bdef-40f9-94da-b3908a1fa3c2
dc.identifier 10.2174/0929867323666160428105849
dc.identifier https://avesis.sdu.edu.tr/publication/details/97642b8e-bdef-40f9-94da-b3908a1fa3c2/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/93471
dc.description Mitochondria play a critical role in regulating cellular functions, such as redox signaling, calcium homeostasis, and apoptosis. Also, mitochondria are crucial for neurogenesis and neuronal functions. Melatonin is an indole analog hormone, which is generally produced by the pineal gland. It plays a vital role in circadian rhythm and act as a powerful antioxidant by scavenging free radicals, immunomodulators, and anticancer agents. Schizophrenia and mood disorders are the two major psychiatric disorders. Disturbances of sleep and circadian rhythms are well-known symptoms of schizophrenia and mood disorders (bipolar disorder, major depression). Since melatonin has a regulator effect on circadian rhythm and sleep quality, it has a close interaction with schizophrenia and mood disorders. Herein, we aimed to summarize the effects of melatonin on mitochondrial activity in schizophrenia and mood disorders.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The Importance of Melatonin and Mitochondria Interaction in Mood Disorders and Schizophrenia: A Current Assessment
dc.type info:eu-repo/semantics/article


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