| dc.creator |
Kanter, M |
|
| dc.creator |
Bapci, Z |
|
| dc.creator |
Karaoz, E |
|
| dc.date |
2002-01-01T01:00:00Z |
|
| dc.date.accessioned |
2021-12-03T11:46:17Z |
|
| dc.date.available |
2021-12-03T11:46:17Z |
|
| dc.identifier |
a1cc7978-a62d-4e1c-a319-73eb69c54c89 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/a1cc7978-a62d-4e1c-a319-73eb69c54c89/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/93827 |
|
| dc.description |
This experiment was carried out to demonstrate the effect of moclobemide on the brains of rats fed on a diet containing alcohol. Thirty male rats, 200250 g were used. Rats were fed with a diet (milk) containing ethyl alcohol (10%) in the alcohol-only treated group and were injected subcutaneously with moclobemide (30 mg/kg) in the alcohol+moclobemide treated group daily for 21 days. It is found that the serum ethanol level in the alcohol+moclobemide treated group was significantly higher than in alcohol-only treated group at the end of the experiment. Electron microscopic examination revealed more prominent neurotoxicity in the alcohol+moclobemide treated group than in alcohol-only treated group. We concluded that moclobemide decreases the elimination of ethanol. However, more studies are needed to demonstrate its mechanism. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
The effect of moclobemide, reversible inhibitor of monoamine oxidase-A, on the alcoholized rat brain |
|
| dc.type |
info:eu-repo/semantics/article |
|