| dc.creator |
TÜRER CABBAR, Ayça; YEDITEPE UNIVERSITY, FACULTY OF MEDICINE |
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| dc.creator |
ŞIMŞEK, Mustafa Aytek; YEDITEPE UNIVERSITY, FACULTY OF MEDICINE |
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| dc.creator |
HÜNÜK, Burak; YEDITEPE UNIVERSITY, FACULTY OF MEDICINE |
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| dc.creator |
ÖZVEREN, Olcay; YEDITEPE UNIVERSITY, FACULTY OF MEDICINE |
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| dc.creator |
GÜZELBURÇ, Özge; İSTANBUL DR. SİYAMİ ERSEK GÖĞÜS KALP VE DAMAR CERRAHİSİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ |
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| dc.creator |
DEĞERTEKIN, Muzaffer; YEDITEPE UNIVERSITY, FACULTY OF MEDICINE |
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| dc.date |
2021-09-13T00:00:00Z |
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| dc.date.accessioned |
2021-12-03T11:46:51Z |
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| dc.date.available |
2021-12-03T11:46:51Z |
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| dc.identifier |
https://dergipark.org.tr/tr/pub/sdutfd/issue/64881/820120 |
|
| dc.identifier |
10.17343/sdutfd.820120 |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/94082 |
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| dc.description |
ObjectiveSince many studies focused on the relationshipbetween mean platelet volume (MPV) and severity oftype 2 diabetes mellitus (T2DM) or investigated MPVand coronary artery disease (CAD) mostly on acutecoronary syndrome (ACS), this study primarily focusedto investigate if MPV values have any relation withdifferent levels of CAD specifically in T2DM patients,who had no previous coronary artery disease, and noACS history.Materials And MethodsT2DM patients who had first coronary angiography(CAG) between November 2019 and February2020, and whose after night fasting blood testswere performed before CAG were included. Twocardiologists, blinded to the patients, evaluatedangiographies. Patients have divided into groupsaccordingly; normal coronary artery (Group 1),non-critic stenosis (Group II), and severe CAD(Group III) according to the Gensini score. Patients’demographics, heart rate, risk factors of CAD, andblood test including MPV were also collected.ResultsA total of 180 patients (88 female, 92 male) wereinvolved in the study. There was no significant relationbetween MPV and the severity of CAD in T2DMpatients (p=0.228). The mean age of the Group I groupwas significantly lower than in other groups (p=0.228),and there were significantly lower males in Group Ithan other groups (p=0.0001). The triglycerides levelswere significantly low in Group I than in other groups(p=0.021 and p=0.006).ConclusionMPV values were not associated with the severityof CAD in stable patients. Older age, male gender,higher levels of triglycerides, and initial glucose levelswere significantly related to the severity of CAD inT2DM patients. |
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| dc.description |
AmaçBirçok çalışma, ortalama trombosit hacmi (MPV) iletip 2 diabetes mellitus (T2DM) şiddeti arasındaki ilişkiyeodaklanmakta veya MPV ve koroner arter hastalığı(KAH) çoğunlukla akut koroner sendrom (AKS)hastaları üzerinde gerçekleştirilmektedir. Bu çalışmaöncelikle koroner arter hastalığı ve AKS öyküsü olmayanT2DM hastalarında MPV değerlerinin farklı derecelerdekiKAH ile ilişkisi araştırılmıştır.Gereç ve YöntemKasım 2019 ile Şubat 2020 tarihleri arasında ilk koroneranjiyografi (CAG) yaptıran ve CAG öncesi geceaçlık kan testleri yapılan T2DM hastaları dahil edildi.Anjiyografiler iki kardiyolog değerlendirdi. Hastalar bubulgular ve Gensini skoruna göre; normal koroner arter(Grup 1), kritik olmayan darlık (Grup II) ve ciddiKAH (Grup III) olarak 3 gruba ayrıldı. Hastaların demografikverileri, kalp atış hızı, CAD risk faktörleri veMPV dahil kan testleri değerlendirildi.BulgularÇalışmaya toplam 180 hasta (88 kadın, 92 erkek)dahil edildi. T2DM hastalarında MPV ile KAH şiddetiarasında anlamlı bir ilişki bulunmadı (p=0,228).Grup I grubunun ortalama yaşı diğer gruplardan anlamlıolarak daha düşüktü (p=0,228). Grup I'de diğergruplara göre anlamlı oranda düşük sayıda erkekvardı (p=0,0001). Trigliserid düzeyleri Grup I'de diğergruplara göre anlamlı olarak düşüktü (p=0,021 vep=0,006).SonuçMPV değerleri stabil hastalarda KAH şiddeti ile ilişkilibulunmadı. T2DM hastalarında ileri yaş, erkek cinsiyet,yüksek trigliserit seviyeleri ve başlangıç glikoz seviyeleri,KAH şiddeti ile önemli ölçüde ilişkiliydi. |
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| dc.format |
application/pdf |
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| dc.language |
en |
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| dc.publisher |
Süleyman Demirel Üniversitesi |
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| dc.publisher |
Süleyman Demirel University |
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| dc.relation |
https://dergipark.org.tr/tr/download/article-file/1376552 |
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| dc.source |
Volume: 28, Issue: 3
411-417 |
en-US |
| dc.source |
1300-7416 |
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| dc.source |
2602-2109 |
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| dc.source |
SDÜ Tıp Fakültesi Dergisi |
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| dc.subject |
Coronary artery disease,mean platelet volume,type 2 diabetes mellitus |
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| dc.subject |
Koroner arter hastalığı,ortalama trombosit hacmi,tip 2 diabetes mellitus |
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| dc.title |
EVALUATION OF THE RELATIONSHIP BETWEEN MPV AND SEVERITY OF CORONARY ARTERY DISEASE IN TYPE 2 DIABETIC PATIENTS WITHOUT ACUTE CORONARY SYNDROME |
en-US |
| dc.title |
AKUT KORONER SENDROM OLMAYAN TİP 2 DİYABETİK HASTALARDA KORONER ARTER HASTALIĞI YAYGINLIĞI İLE MPV İLİŞKİSİNİN ARAŞTIRILMASI |
tr-TR |
| dc.type |
info:eu-repo/semantics/article |
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