| dc.creator |
SELÇUK, Esma; SÜLEYMAN DEMİREL ÜNİVERSİTESİ, TIP FAKÜLTESİ |
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| dc.creator |
ALSAMMARRAIE, Hanan; SÜLEYMAN DEMİREL ÜNİVERSİTESİ, TIP FAKÜLTESİ |
|
| dc.date |
2021-06-05T00:00:00Z |
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| dc.date.accessioned |
2021-12-03T11:47:01Z |
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| dc.date.available |
2021-12-03T11:47:01Z |
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| dc.identifier |
https://dergipark.org.tr/tr/pub/sdutfd/issue/62643/863761 |
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| dc.identifier |
10.17343/sdutfd.863761 |
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| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/94220 |
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| dc.description |
Koronavirüs hastalığı (Covid-19), ilk olarak Aralık 2019'da Çin'in Hubei eyaletinde bildirilen, sistemik bir solunum yolu hastalığıdır. Covid-19, 11 Mart 2020'de Dünya Sağlık Örgütü tarafından küresel bir pandemi ilan edilmiş ve dünya çapında yüz binlerce insanın ölümüne neden olmuştur. Covid-19, Wuhan şehrindeki hayvan pazarlarında ortaya çıkan, RNA beta koronavirüsü olan yeni şiddetli akut solunum sendromu koronavirüs 2'den (SARS-COV-2) kaynaklanmaktadır. İnsanlarda Covid-19, hava yoluyla kişiden kişiye bulaşan son derece bulaşıcı bir hastalıktır. Yaş kriteri olmaksızın insanları enfekte etme kabiliyetine sahip olan Covid-19, kronik rahatsızlıkları olan hastaların morbidite ve mortalitesinde ciddi bir etkiye sahiptir. Kronik olarak bağışıklık sistemi baskılanması nedeniyle genel popülasyona kıyasla böbrek nakli alıcılarında (KTR), Covid-19 ciddi komplikasyon riskini attırmaktadır. Covid-19’lu KTR’ler genel popülasyona benzer şekilde hafif, orta ve şiddetli olarak klinik belirtiler göstermektedir. Fakat daha ağır seyrinin olabileceği de literatürde mevcuttur. Covid-19’lu KTR’lerde immünsüpresif (IS) ilaçların kullanımının azaltılmasının yarar sağladığı görülmüştür. Antiviral kullanım etkisi ise kişiden kişiye değişiklik göstermektedir. Literatür verilerine göre Covid-19’lu KTR’lerde lenfopeni görülürken IL-6 seviyesinde önemli ölçüde yükselme kaydedilmiştir. Aşı ve deney hayvanları çalışması ise literatürde mevcut değildir. |
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| dc.description |
Coronavirus disease (Covid-19) is a systemic respiratory illness first reported in Hubei province of China in December 2019. Covid-19 was declared a global pandemic by the World Health Organization on March 11, 2020, causing the deaths of hundreds of thousands of people worldwide. Covid-19 is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), the RNA beta coronavirus, that appears in animal markets in Wuhan city. In humans, Covid-19 is a highly contagious disease that is transmitted from person to person by air. Covid-19, which has the ability to infect humans without age criteria, has a serious impact on the morbidity and mortality of patients with chronic diseases. Due to chronic immune system suppression In kidney transplant recipients (CTR) compared to the general population, Covid-19 increases the risk of serious complications. CTRs with Covid-19 show clinical symptoms such as mild, moderate and severe similar to the general population. However, it is also available in the literature that it may have a more severe course. It has been observed that it is beneficial in reducing the use of immunosuppressive (IS) drugs in CTRs with Covid-19. The use of antiviral effects varies from person to person. According to the literature data, while lymphopenia was seen in CTRs with Covid-19, a significant increase in IL-6 level was recorded. Vaccine and experimental animal studies are not available in the literature. In this review, it is aimed to discuss the role, epidemiology and symptoms of Covid-19 in CTRs. |
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| dc.format |
application/pdf |
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| dc.language |
tr |
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| dc.publisher |
Süleyman Demirel Üniversitesi |
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| dc.publisher |
Süleyman Demirel University |
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| dc.relation |
https://dergipark.org.tr/tr/download/article-file/1518209 |
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| dc.source |
Volume: COVID-19 Özel Sayı, Issue: 1
73-78 |
en-US |
| dc.source |
1300-7416 |
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| dc.source |
2602-2109 |
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| dc.source |
SDÜ Tıp Fakültesi Dergisi |
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| dc.subject |
Covid-19,KTR,ACE2 Enzimi |
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| dc.subject |
Covid-19,CTR,ACE2 Enzyme |
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| dc.title |
Böbrek Nakli Alıcılarında Korona Virüsün (COVID-19) Etkisi |
tr-TR |
| dc.title |
Effect of Corona Virus (COVID-19) in Kidney Transplant Recipients |
en-US |
| dc.type |
info:eu-repo/semantics/article |
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