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Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats

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dc.creator Tamer, Mehmet Numan
dc.creator Dal, Mehmet Sinan
dc.creator GÖKALP, OSMAN
dc.creator BÜYÜKBAYRAM, HÜSEYİN
dc.creator Cim, Abdullah
dc.creator KAYA, SAVAŞ
dc.creator Firat, Ugur
dc.date 2012-01-01T01:00:00Z
dc.date.accessioned 2021-12-03T11:47:02Z
dc.date.available 2021-12-03T11:47:02Z
dc.identifier ae07247a-797d-4039-ab54-54fe626c69ff
dc.identifier 10.1155/2012/316384
dc.identifier https://avesis.sdu.edu.tr/publication/details/ae07247a-797d-4039-ab54-54fe626c69ff/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/94232
dc.description Eryptosis is a term to define apoptosis of erythrocytes. Oxidative stress and hyperglycemia, both of which exist in the diabetic intravascular environment, can trigger eryptosis of erythrocytes. In this experimental study, it is presented that the majority of erythrocytes shows caspase-3 immunoreactivity in streptozocin- (STZ)-induced diabetic rats. Besides that, caspase-3 positive erythrocytes are aggregated and attached to vascular endothelium. In conclusion, these results may start a debate that eryptosis could have a role in the diabetic complications.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats
dc.type info:eu-repo/semantics/article


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