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LACTATE LEVEL IN STABLE COPD PATIENTS

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dc.creator PIHTILI, Aylin; İSTANBUL ÜNİVERSİTESİ, İSTANBUL TIP FAKÜLTESİ
dc.creator MAMMADOVA, Konul; İSTANBUL ÜNİVERSİTESİ, İSTANBUL TIP FAKÜLTESİ
dc.creator KIYAN, Esen; İSTANBUL ÜNİVERSİTESİ, İSTANBUL TIP FAKÜLTESİ
dc.date 2021-09-13T00:00:00Z
dc.date.accessioned 2021-12-03T11:47:03Z
dc.date.available 2021-12-03T11:47:03Z
dc.identifier https://dergipark.org.tr/tr/pub/sdutfd/issue/64881/822908
dc.identifier 10.17343/sdutfd.822908
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/94248
dc.description ObjectiveLactate level is an indicator of tissue oxygenation.It might be valuable for COPD patients to havea prognostic marker. Thus, we aimed to evaluatethe relationship between lactate level and COPDclassification, FEV1 level, exacerbations, hypoxemiain stable COPD patients.Materials and MethodsIn this retrospective study, demographics, arterialblood gas analysis, exacerbation history, GOLDclassification, pulmonary function tests, long-termoxygen therapy (LTOT) and non-invasive mechanicalventilation (NIMV) usage in stable COPD patientswere recorded.ResultsTotally 103 patients (M / F: 90/13, mean age: 66.8 ±8.0years) were included. Mean FEV1:45±20%, FVC:63±22%, PaO2:66±15mmHg, PaCO2:43±8mmHg,lactate level: 1.5±0.6mmol/L. The groups of thepatients according to GOLD COPD classification wereas follows;; 11.7%, 15.5%, 24.3%, 48.5% in A,B,C,D,respectively. Of patients 47.6% were using LTOT and37.3% were using NIMV. Lactate level of the patientsin category D was significantly higher than the patientsin A, B, C categories (p
dc.description AmaçMorbidite ve mortalitesi yüksek olan KOAH’da, prognostikbelirteçlerin saptanması önemlidir. Plazma laktatdüzeyi, doku oksijen ihtiyacını gösteren ve kolayulaşılabilen bir tetkiktir. Çalışmamızın amacı; stabilKOAH olgularında plazma laktat düzeyi ile GOLDKOAH kategorisi, FEV1, ataklar ve hipoksemi arasındakiilişkiyi incelemektir.Gereç ve YöntemGöğüs Hastalıkları Polikliniği’ne başvuran stabil dönemdekiKOAH olguları retrospektif olarak değerlendirildi.Demografik özellikler, arter kan gazı analizleri,yıllık atak sayıları, GOLD KOAH kategorisine göre;A,B,C,D sınıfları, spirometrik parametreler, evde uzunsüreli oksijen tedavisi (USOT) ve non-invaziv mekanikventilasyon (NİMV) kullanıp kullanmadıkları kaydedildi.BulgularToplam 103 stabil KOAH olgusu (E/K: 90/13, ortalamayaş: 66.8±8.0/yıl) çalışmaya dahil edildi. OlgularınFEV1:%45.7±20.2, FVC:%63.5±22.2, Pa-O2:66.3±15.0mmHg, PaCO2:43.9±8.3mmHg, laktat:1.5±0.6 mmol/L idi. On iki olgu(%11.7) A, 16 olgu(%15.5) B, 25 olgu (%24.3) C, 50 olgu (%48.5) D grubundaidi. Olguların %47.6’sı (n=49) USOT, %37.3’ü(n=28) NİMV kullanmakta idi. D kategorisindeki olgulardalaktat düzeyi A, B, C sınıflarına göre belirginyüksekti (p
dc.format application/pdf
dc.language tr
dc.publisher Süleyman Demirel Üniversitesi
dc.publisher Süleyman Demirel University
dc.relation https://dergipark.org.tr/tr/download/article-file/1385947
dc.source Volume: 28, Issue: 3 427-432 en-US
dc.source 1300-7416
dc.source 2602-2109
dc.source SDÜ Tıp Fakültesi Dergisi
dc.subject GOLD,COPD,lactate level
dc.subject GOLD,KOAH,laktat düzeyi
dc.title LACTATE LEVEL IN STABLE COPD PATIENTS en-US
dc.title STABİL KOAH OLGULARINDA PLAZMA LAKTAT DÜZEYİ tr-TR
dc.type info:eu-repo/semantics/article
dc.citation Referans 1: Neumeier A, Keith R. Clinical Guideline Highlights for the Hospitalist: The GOLD and NICE Guidelines for the Management of COPD. J Hosp Med. 2020;15(4):240-41.
dc.citation Referans 2: Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020. Available from: http://www.goldcopd.org/
dc.citation Referans 3:Jansen TC, van Bommel J, Bakker J. Blood lactate monitoring in critically ill patients: a systematic health technology assessment. Crit Care Med. 2009; 37(10):2827–39
dc.citation Referans 4: Crawford SO, Ambrose MS, Hoogeveen RC, Brancati FL, Ballantyne CM, Young JH. Association of lactate with blood pressure before and after rapid weight loss. Am J Hypertens. 2008; 21(12):1337–42.
dc.citation Referans 5: Zagari F, Jordan M, Stettler M, Zagari F, Jordan M, Stettler M, Broly H, Wurm FM. Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity. N Biotechnol. 2013; 30(2):238–45.
dc.citation Referans 6:Shapiro NI, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, et al. A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis. Crit Care Med. 2009; 37(1):96-104
dc.citation Referans 7:Vincent JL, Quintairos E Silva A, Couto Jr L, Taccone FS. The value of blood lactate kinetics in critically ill patients: a systematic review. Crit Care 2016; 20(1):257.
dc.citation Referans 8: Zhang Z, Xu X. Lactate clearance is a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review and meta-analysis. Crit Care Med 2014; 42(9):2118–25.
dc.citation Referans 9: Haas SA, Lange T, Saugel B, Petzoldt M, Fuhrmann V, Metschke M, et al. Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients. Intensive Care Med. 2016; 42(2):202–10
dc.citation Referans 10: Galić K, Pravdić D, Prskalo Z, Kukulj S, Starčević B, Vukojević M. Prognostic value of lactates in relation to gas analysis and acid-base status in patients with pulmonary embolism. Croat Med J. 2018; 59(4):149-55.
dc.citation Referans 11: Nguyen HB, Rivers EP, Knoblich BP, Jacobsen G, Muzzin A, Ressler JA, et al.Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med. 2004; 32(8):1637-42
dc.citation Referans 12: Nichol AD, Egi M, Pettila V, Bellomo R, French C, Hart G, et al. Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study. Crit Care 2010; 14(1):25.
dc.citation Referans 13: Durmuş U, Doğan NÖ, Pekdemir M, Yılmaz S, Yaka E, Karadaş A, et al.The value of lactate clearance in admission decisions of patients with acute exacerbation of COPD. Am J Emerg Med. 2018 ; 36(6):972-76
dc.citation Referans 14:Brasil Santos D, de Assis Viegas CA. Correlation of levels of obstruction in COPD with lactate and six-minute walk test. Rev Port Pneumol. 2009; 15(1):11-25.
dc.citation Referans 15:Tanaka Y, Hino M, Morikawa T, Takeuchi K, Mizuno K, Kudoh S. Arterial blood lactate is a useful guide to when rehabilitation should be instigated in COPD. Respirology. 2008; 13(4):564-8.
dc.citation Referans 16:Skjørten I, Hilde JM, Melsom MN, Hisdal J, Hansteen V, Steine K, et al. Exercise capacity in COPD patients with exercise-induced pulmonary hypertension. Int J Chron Obstruct Pulmon Dis. 2018; 13:3599-610.
dc.citation Referans 17:Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yemault JC. Lung volumes and forced ventilatory flows.Report working party standardization of lung function tests, European community for steel and coal.Official statement of the European respiratory society. Eur Respir J Suppl. 1993; 16:5–40


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