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ÇOCUKLUK ÇAĞI COVID-19 HASTALIĞINDA HEMATOLOJİK BULGULAR VE ANTİKOAGÜLAN KULLANIMI

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dc.creator YILMAZ, Ebru; SÜLEYMAN DEMİREL ÜNİVERSİTESİ
dc.date 2021-06-05T00:00:00Z
dc.date.accessioned 2021-12-03T11:47:05Z
dc.date.available 2021-12-03T11:47:05Z
dc.identifier https://dergipark.org.tr/tr/pub/sdutfd/issue/62643/907236
dc.identifier 10.17343/sdutfd.907236
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/94267
dc.description Ağır akut respiratuvar sendrom koronavirüs-2 (SARS-CoV-2) ajanının yol açtığı Koronavirüs-2019 hastalığı (COVID-2019), bir solunum yolu hastalığı olarak düşünülmekle birlikte, birçok sistemde etkilenmeye yol açabilir. Bu olgularda hematolojik komplikasyonlar izlenebilir. Erişkin COVID-19 hastalarında lenfopeni ve hiperkoagülabilite bildirilmiştir ve bunların varlığı kötü prognoz ile ilişkilendirilmiştir. Pediatrik COVID-19 olgularında izlenen hematolojik bulguların erişkinlerden farklı özellikler gösterebildiği kaydedilmiştir. Gözlemsel çalışmalar, COVID-19 ilişkili hastalık nedeniyle hastaneye yatırılan çocuklarda, erişkinlerdeki gibi, venöz tromboembolizm riskinin arttığına işaret etmektedir. Ancak, etkilenen olgularda antikoagülan tromboprofilaksi önerilerini içeren rehberler ağırlıklı olarak erişkin hastalar için oluşturulmuştur. Bu derlemede SARS-CoV-2 enfeksiyonu olan çocukların hematolojik bulgularının gözden geçirilmesi ve etkilenen çocuklarda kanıta dayalı antikoagülan tromboprofilaksi önerilerinin sunulması amaçlanmıştır.
dc.description Coronavirus disease 2019 (COVID-2019) caused by severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), though mainly affecting the respiratory system, may cause manifestations in multiple organ systems, e.g. hematological complications may be observed in affected individuals. Lymphopenia and hypercoagulability have been reported in adult COVID-19 patients, and have been associated with a poor prognosis. Hematological findings observed in pediatric COVID-19 cases have been reported to differ from those seen in adults. Observational studies in children with a COVID-19-related illness have pointed, like in adults, to an increased risk for venous thromboembolism. However, guidelines including recommendations for anticoagulant thromboprophylaxis in COVID-19 patients have mainly been developed for adult population. This review summarizes the hematological manifestations of children with SARS-CoV-2 infection, and presents evidence-based recommendations for anticoagulant thromboprophylaxis in affected children.
dc.format application/pdf
dc.language tr
dc.publisher Süleyman Demirel Üniversitesi
dc.publisher Süleyman Demirel University
dc.relation https://dergipark.org.tr/tr/download/article-file/1675536
dc.source Volume: COVID-19 Özel Sayı, Issue: 1 61-66 en-US
dc.source 1300-7416
dc.source 2602-2109
dc.source SDÜ Tıp Fakültesi Dergisi
dc.subject Çocuklar,SARS-CoV-2,COVID-19,Hematolojik bulgular,Venöz tromboembolizm,Tromboprofilaksi
dc.subject Children,SARS-CoV-2,Hematological manifestations,Venous thromboembolism,Thromboprophylaxis
dc.title ÇOCUKLUK ÇAĞI COVID-19 HASTALIĞINDA HEMATOLOJİK BULGULAR VE ANTİKOAGÜLAN KULLANIMI tr-TR
dc.title HEMATOLOGICAL MANIFESTATIONS AND ANTICOAGULANT USE IN CHILDREN WITH COVID-19 DISEASE en-US
dc.type info:eu-repo/semantics/article
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