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Diagnostic ultrasound treatment increases the bone fracture-healing rate in an internally fixed rat femoral osteotomy model

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dc.creator Yesildag, A
dc.creator Mumcu, EF
dc.creator Tekinsoy, MA
dc.creator Gulsoy, UK
dc.creator Oyar, O
dc.creator Heybeli, N
dc.date 2002-12-01T01:00:00Z
dc.date.accessioned 2021-12-03T11:53:51Z
dc.date.available 2021-12-03T11:53:51Z
dc.identifier b3254c67-d051-47b6-b642-83e88c5e2feb
dc.identifier 10.7863/jum.2002.21.12.1357
dc.identifier https://avesis.sdu.edu.tr/publication/details/b3254c67-d051-47b6-b642-83e88c5e2feb/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/94371
dc.description Objective. To investigate the healing effects of diagnostic ultrasound in a standardized rat femur fracture model. Methods. Thirty-two male rats aged 14 weeks were used, and each rat's right femur was osteotomized and stabilized under anesthesia, The rats were then divided into 4 groups, Five days after surgery, ultrasound was applied every fifth day with diagnostic sonographic equipment and a probe with a 7.5-MHz frequency and 11.8-mW/cm(2) total output intensity for 10 minutes in each session. Ultrasound was applied 8 times in group A, 3 times in group 3, and only once in group C, Ultrasound was not applied to sham-operated group D. Healing and callus formation of the rats' femur fractures were evaluated by radiography and dual-energy x-ray absorptiometry. Results. Dual-energy x-ray absorptiometric and radiographic results showed that the ultrasound therapy accelerated the fracture healing. Radiographically, groups A and B showed better fracture healing than groups C and D, Ultrasound exposure increased both the whole-bone mineral density and the density at the fracture region, increasing in parallel with the exposure period. Conclusions. This study confirms the previously shown efficacy of low-intensity ultrasonic stimulation in acceleration of the normal fracture repair process even when performed with a diagnostic sonographic device.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Diagnostic ultrasound treatment increases the bone fracture-healing rate in an internally fixed rat femoral osteotomy model
dc.type info:eu-repo/semantics/article


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