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The effect of G-CSF and Teicoplanin in an experimental MRSA graft infection in mice

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dc.creator Agalar, F
dc.creator Sari, A
dc.creator Sari, M
dc.creator Eroglu, E
dc.creator Agalar, C
dc.date 2000-01-01T01:00:00Z
dc.date.accessioned 2021-12-03T11:54:49Z
dc.date.available 2021-12-03T11:54:49Z
dc.identifier c441ad29-1721-4a0c-8959-df272729ca98
dc.identifier https://avesis.sdu.edu.tr/publication/details/c441ad29-1721-4a0c-8959-df272729ca98/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/94743
dc.description G-CSF and Teicoplanin were studied in an experimental methicilline resistant staphylococcal graft infection model. An incision in 2 cm in length and a cavity in 2x2 cm in length was performed. Polypropylene mesh and MRSA solution of 0.1 mi of 10(8) CFU/ml were used. G-CSF or teicoplanin was applied systemically or locally in different settings. Three days from the operation incisions were examined for a possible infection. Under sterile conditions meshes were removed. Following one minute vortexing, dilution scheme was performed. When the wounds were examined it was seen that there were symptoms of wound infection in all groups except group VIII, In group VIII MRSA was isolated in 7 events with a colony count below 10(3), G-CSF could not prevent the development of wound infection, but Teicoplanin decreased the numbers of colony forming units of MRSA, and prevents wound infection in this MRSA wound infection model.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The effect of G-CSF and Teicoplanin in an experimental MRSA graft infection in mice
dc.type info:eu-repo/semantics/conferenceObject


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