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Functional components, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of Salvia syriaca L.

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dc.creator Movahhedin, Nasrin
dc.creator Asghari, Behvar
dc.creator Bahadori, Shahram
dc.creator Sarikurkcu, Cengiz
dc.creator Zengin, Gokhan
dc.creator Dinparast, Leila
dc.creator Bahadori, Mir Babak
dc.date 2017-01-01T00:00:00Z
dc.date.accessioned 2021-12-03T12:03:11Z
dc.date.available 2021-12-03T12:03:11Z
dc.identifier d402748e-6209-4adf-bbe7-426773eb4586
dc.identifier 10.1080/10942912.2016.1218893
dc.identifier https://avesis.sdu.edu.tr/publication/details/d402748e-6209-4adf-bbe7-426773eb4586/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/95096
dc.description Antidiabetic, anti-Alzheimer, general toxicity, and antioxidant activities of Salvia syriaca were evaluated. Phytochemical composition of the essential oil and methanolic extract of the plant were identified using gas chromatography-mass spectrometry and reverse-phase high-performance liquid chromatography-diode array detector techniques, respectively. Essential oil of S. syriaca exhibited strong cytotoxicity, antioxidant, a-amylase, and a-glucosidase inhibitory activities. Gas chromatography-mass spectrometry analysis showed that spathulenol (87.4%), isospathulenol (7.6%), and bornyl acetate (2.7%) are the major compounds in essential oil. High-performance liquid chromatography analysis indicated that rutin, quercetin, apigenin, rosmarinic acid, and ferulic acid are the most abundant phenolic components. S. syriaca could be considered as a valuable source of bioactive natural compounds for functional foods, medical, and pharmaceutical applications.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Functional components, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of Salvia syriaca L.
dc.type info:eu-repo/semantics/article


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