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Dendritic cell sarcomas/tumours of the breast: report of two cases

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dc.creator Kapucuoglu, Nilgun
dc.creator Eusebi, Vincenzo
dc.creator Al-Daraji, Wael
dc.creator Lang, RongGang
dc.creator Ventura, Terenzio
dc.creator Percinel, Sibel
dc.date 2009-03-01T01:00:00Z
dc.date.accessioned 2021-12-03T12:04:27Z
dc.date.available 2021-12-03T12:04:27Z
dc.identifier e8be5683-d209-4a4e-9d6b-8e41bc7d3113
dc.identifier 10.1007/s00428-009-0729-7
dc.identifier https://avesis.sdu.edu.tr/publication/details/e8be5683-d209-4a4e-9d6b-8e41bc7d3113/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/95568
dc.description Extranodal follicular dendritic cell sarcoma/tumours (FDCS/Ts) and interdigitating dendritic cell sarcoma/tumours (IDCS/Ts) are rare neoplasms. We present two cases of FDCS/T and IDCS/T of the breast. The FDCS/T case (case 1) presented in a 31-year-old woman and the IDCS/T case (case 2) in a 67-year-old woman who both showed a firm lump in the left breast. The FDCS/T lesion superficially appeared as an anaplastic carcinoma and the IDCS/T was reminiscent of a spindle cell sarcomatoid carcinoma. Nevertheless both lesions were negative for keratins while case 1 displayed neoplastic cells strongly positive for CD21, vimentin and focally for CD68 and S-100 protein. The tumour cells of case 2 were positive for S-100, CD68 and CD45. In breast, an unusual keratin negative tumour composed predominantly of spindle cells arranged in fascicles, storiform pattern or whorls with a lymphoid rich stroma should raise suspicion for FDCS/Ts or IDCS/Ts. The distinction from malignant tumours with similar features is discussed.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Dendritic cell sarcomas/tumours of the breast: report of two cases
dc.type info:eu-repo/semantics/article


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