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Screening of Possible In Vitro Neuroprotective, Skin Care, Antihyperglycemic, and Antioxidative Effects of Anchusa undulata L. subsp. hybrida (Ten.) Coutinho from Turkey and Its Fatty Acid Profile

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dc.creator CEYLAN, OLCAY
dc.creator Sarikurkcu, Cengiz
dc.creator Zengin, Gokhan
dc.creator Aktumsek, Abdurrahman
dc.creator Uysal, Sengul
dc.date 2015-07-03T00:00:00Z
dc.date.accessioned 2021-12-03T12:04:45Z
dc.date.available 2021-12-03T12:04:45Z
dc.identifier ed71f7de-1920-4610-aa75-dcb210783b0c
dc.identifier 10.1080/10942912.2014.913182
dc.identifier https://avesis.sdu.edu.tr/publication/details/ed71f7de-1920-4610-aa75-dcb210783b0c/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/95683
dc.description The aim of this work was to determine antioxidant capacities, neuroprotective, skin care, antidiabetic effects, and fatty acid composition of Anchusa undulata subsp. hybrida. The antioxidant activity was screened by four different test systems including total antioxidant, antiradical, reducing power, and metal chelating activities. Neuroprotective potential was determined by anticholinesterase inhibitor assay. Tyrosinase inhibitory activity was tested to detect skin care effect. Antidiabetic effects were evaluated with alpha-amylase and alpha-glucosidase inhibitory assays. Inhibitory activities on acetycholinesterase, butyrylcholinesterase, tyrosinase, alpha-amylase, and alpha-glucosidase enzymes were observed as 2.238 and 1.239 mu mol GALAEs/g, 0.339 mmol KAEs/g, 0.193, and 0.219 mmol ACEs/g extract, respectively. Amount of total phenolics and flavonoids were found as 80.34 mu g GAEs/mg and 25.09 mu g QEs/mg in the extract, respectively. Twenty-three fatty acids were found in the aerial parts, being oleic acid (24.30 g/100 g of total fatty acids) the most abundant, followed by linoleic (21.19 g/100 g of total fatty acids) and palmitic acids (17.50 g/100 g of total fatty acids).
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Screening of Possible In Vitro Neuroprotective, Skin Care, Antihyperglycemic, and Antioxidative Effects of Anchusa undulata L. subsp. hybrida (Ten.) Coutinho from Turkey and Its Fatty Acid Profile
dc.type info:eu-repo/semantics/article


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