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KLOTHO and VDR Gene Polymorphisms and Clinical Phenotype in Chronic Kidney Disease Patients

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dc.creator Ozturk, Kuyas Hekimler
dc.creator Yildiz, Saliha Handan
dc.creator Imirzalioglu, Necat
dc.creator Demir, Serap
dc.creator KÖKEN, TÜLAY
dc.creator ULU, MEMNUNE SENA
dc.date 2019-01-01T00:00:00Z
dc.date.accessioned 2021-12-03T12:05:01Z
dc.date.available 2021-12-03T12:05:01Z
dc.identifier f24df95e-2781-470a-ae2f-59c36c36560d
dc.identifier 10.12996/gmj.2019.04
dc.identifier https://avesis.sdu.edu.tr/publication/details/f24df95e-2781-470a-ae2f-59c36c36560d/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/95788
dc.description Objective: With an increasing incidence and prevalence, Chronic Kidney Disease (CKD), is a bad prognosed and high cost common public health problem. KLOTHO gene which is defined as aging suppressor gene is highly expressed in kidneys. Decreased Vitamin D receptor (VDR) activation plays a role in CKD morbidity and mortality. The aim of this study is to examine the association between CKD and polymorphisms of KLOTHO (G395A and C1818T) and VDR (Apal and Taql) genes as well as investigating the effects of these polymorphisms on different clinical phenotype of the disease.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title KLOTHO and VDR Gene Polymorphisms and Clinical Phenotype in Chronic Kidney Disease Patients
dc.type info:eu-repo/semantics/article


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