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Relationship Between Elevated Morning Blood Pressure Surge, Uric Acid, and Cardiovascular Outcomes in Hypertensive Patients

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dc.creator Turak, Osman
dc.creator ÇALIŞKAN, MUSTAFA
dc.creator Covic, Adrian
dc.creator Siriopol, Dimitrie
dc.creator Oksuz, Fatih
dc.creator Mendi, Mehmet Ali
dc.creator Grbovic, Enis
dc.creator CANPOLAT, UĞUR
dc.creator Ozcan, Firat
dc.creator Afsar, Barış
dc.creator McFann, Kim
dc.creator Kanbay, Mehmet
dc.creator Johnson, Richard J.
dc.date 2014-07-01T00:00:00Z
dc.date.accessioned 2021-12-03T12:05:44Z
dc.date.available 2021-12-03T12:05:44Z
dc.identifier fe612f56-91e5-4c4a-969e-897c2f0c7018
dc.identifier 10.1111/jch.12359
dc.identifier https://avesis.sdu.edu.tr/publication/details/fe612f56-91e5-4c4a-969e-897c2f0c7018/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96055
dc.description Early morning blood pressure surge (MBPS) is a risk factor for cardiovascular events (CVEs), but the relationship with uric acid is not well understood. The authors aimed to determine the association between MBPS and increased uric acid and the effect of elevated MBPS and uric acid combination on CVEs. A total of 921 patients underwent 24-hour ambulatory blood pressure monitoring and were followed for a median of 40 months. During this period, 103 (11.2%) CVEs occurred. There was a significant relationship between increasing quartiles of serum uric acid level and increasing values of MBPS (P<.0001). Patients in the highest quartile stratified by elevated MBPS and serum uric acid level had a 3.55 odds of major CVE compared with patients in the lowest quartile. Serum uric acid is associated with MBPS and development of new CVEs. (C) 2014 Wiley Periodicals, Inc.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Relationship Between Elevated Morning Blood Pressure Surge, Uric Acid, and Cardiovascular Outcomes in Hypertensive Patients
dc.type info:eu-repo/semantics/article


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