| dc.creator |
Aktumsek, Abdurrahman |
|
| dc.creator |
Zengin, Gokhan |
|
| dc.creator |
Sarikurkcu, Cengiz |
|
| dc.creator |
Ceylan, Ramazan |
|
| dc.creator |
Kocak, Mehmet Sefa |
|
| dc.creator |
Uysal, Sengul |
|
| dc.creator |
UYAR, PEMBEGÜL |
|
| dc.date |
2015-08-01T00:00:00Z |
|
| dc.date.accessioned |
2021-12-03T12:05:45Z |
|
| dc.date.available |
2021-12-03T12:05:45Z |
|
| dc.identifier |
fee93945-d5d5-4f1c-9015-6e32e4a273e9 |
|
| dc.identifier |
10.1016/j.jff.2015.06.041 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/fee93945-d5d5-4f1c-9015-6e32e4a273e9/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96063 |
|
| dc.description |
The cytotoxic, anticholinesterase, antityrosinase and antioxidant effects of methanol extract from the flower of C. foetida subsp. rhoeadifolia (CFRME) were evaluated. The cytotoxic effect was investigated using HepG2, Caco-2, MCF-7 and MCF-10A cell lines. Enzyme inhibitory activities were tested by spectrophotometric methods. Different chemical assays were used to determine the antioxidant effects. In addition, phenolic constituents were quantified. High-performance liquid chromatographic (HPLC) analysis revealed that chlorogenic acid was the major phenolic component in the extract. The extract showed a strong antiproliferative, antioxidant, and anticholinesterase and antityrosinase effects. These findings suggest that C. foetida subsp. rhoeadifolia may be considered as a source of ingredients that can be used as food supplements. (C) 2015 Elsevier Ltd. All rights reserved. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Crepis foetida L. subsp rhoeadifolia (Bleb.) Celak. as a source of multifunctional agents: Cytotoxic and phytochemical evaluation |
|
| dc.type |
info:eu-repo/semantics/article |
|