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Meropenem, rifampicin and gentamicin combination therapy in a patient with complicated urinary tract infection caused by extreme drug-resistant P. aeruginosa

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dc.creator FAKIOĞLU, DOLUNAY MERVE
dc.creator ŞENOL, ESİN
dc.creator Albayrak, Aslınur
dc.date 2020-03-01T00:00:00Z
dc.date.accessioned 2022-05-10T11:14:48Z
dc.date.available 2022-05-10T11:14:48Z
dc.identifier 04c4d9d9-7cbc-4da6-b5d3-7e0ef0c7b496
dc.identifier 10.1136/ejhpharm-2019-001873
dc.identifier https://avesis.sdu.edu.tr/publication/details/04c4d9d9-7cbc-4da6-b5d3-7e0ef0c7b496/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96447
dc.description In this article, we report a case of a 25-year-old male patient who was under follow-up for nephrolithiasis and repeated urological interventions. His last operation was carried out 9 months ago for insertion of a double-J catheter. Pseudomonas aeruginosa, which is susceptible to only colistin treatment, was detected in the urine culture. Before the removal of the double-J catheter, colistin and ceftazidime antibiotics were started to prevent the risk of bloodstream infection. However, the treatment was stopped urgently due to signs of nephrotoxicity. His treatment was restarted with colistin 300 mg once as the initial loading dose, followed by 150 mg/day. However, this time, colistin neurotoxicity has developed and the treatment was again stopped. Meropenem 6 g/day, gentamicin 2 mg/kg and rifampicin 300 mg were prescribed. Negative urine culture was achieved on the fifth day of treatment.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Meropenem, rifampicin and gentamicin combination therapy in a patient with complicated urinary tract infection caused by extreme drug-resistant P. aeruginosa
dc.type info:eu-repo/semantics/article


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