| dc.creator |
Keskin, Ebru Yilmaz |
|
| dc.creator |
KESKİN, Mahmut |
|
| dc.creator |
KARAİBRAHİMOĞLU, Adnan |
|
| dc.date |
2022-01-01T00:00:00Z |
|
| dc.date.accessioned |
2022-05-10T11:18:52Z |
|
| dc.date.available |
2022-05-10T11:18:52Z |
|
| dc.identifier |
69220670-38df-4ef4-a109-8d9bc8960f60 |
|
| dc.identifier |
10.1097/mph.0000000000002122 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/69220670-38df-4ef4-a109-8d9bc8960f60/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96686 |
|
| dc.description |
Few studies have examined the association between maternal vitamin B-12 status and their breast-fed infants' findings. The objective of this study was to analyze the association of maternal B-12 status with infant findings including neurodevelopmental outcome in breast-fed babies with B-12 deficiency. Correlation analyses between the laboratory findings of infants with B-12 deficiency (n=120) and their mothers were performed and the association of maternal B-12 status with infant findings including the Denver-II developmental screening test (DDST II) results was examined. There was a significant correlation between infant and maternal B-12 levels (r=0.222; P=0.030), and between infant and maternal homocysteine (Hcy) levels (r=0.390; P<0.001). Among the babies 4 months of age or older, maternal Hcy levels were significantly correlated with infant mean corpuscular hemoglobin (r=0.404; P=0.001) and infant mean corpuscular volume (r=0.461; P<0.001). Mothers of infants with abnormal DDST II had lower vitamin B-12 (196.9 +/- 41.2 vs. 247.0 +/- 77.0 pg/mL; P=0.018) and higher Hcy levels (17.3 +/- 5.0 vs. 10.7 +/- 3.1 mu mol/L; P<0.001) than mothers of infants with normal DDST II. A lower maternal vitamin B-12 status may be related to impaired neurodevelopment in breast-fed infants with vitamin B-12 deficiency. Pregnant and lactating women should be offered easy access to healthy nutrition and vitamin B-12 supplements. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Association of Maternal Vitamin B-12 Status With Infant Findings and Neurodevelopment in Vitamin B-12-Deficient Breast-fed Babies |
|
| dc.type |
info:eu-repo/semantics/article |
|