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New green solutions against bacterial resistance: palmarosa (Cymbopogon martini) essential oil and quorum sensing

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dc.creator Önem, Ebru
dc.date 2022-04-01T00:00:00Z
dc.date.accessioned 2022-05-10T11:19:57Z
dc.date.available 2022-05-10T11:19:57Z
dc.identifier 83e6d4cd-6384-4bf8-b88d-8805e6abebff
dc.identifier 10.1016/j.scp.2021.100587
dc.identifier https://avesis.sdu.edu.tr/publication/details/83e6d4cd-6384-4bf8-b88d-8805e6abebff/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96755
dc.description © 2021This study aimed to determine the phytochemical content of palmarosa (Cymbopogon martini) essential oil and tested for its antibacterial and anti-quorum sensing activity. The possible inhibition effect by molecular modeling was also revealed. It was recorded that geraniol (81.25%) is the main component of palmarosa essential oil and found effective against Gram-positive and Gram-negative bacteria. The essential oil was found to reduce pyocyanin production (by 71%), elastase activity (by 64%), swarming motility (by 69%), and biofilm formation (by 64%). Furthermore, geraniol was docked against the binding region of the LasR protein and found to excellently bound with the receptor. These results showed that palmarosa essential oil acts as a green solution by exerting potential antibacterial activity against most bacteria and has a significant anti-quorum sensing effect on Pseudomonas aeruginosa PAO1 via geraniol.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title New green solutions against bacterial resistance: palmarosa (Cymbopogon martini) essential oil and quorum sensing
dc.type info:eu-repo/semantics/article


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