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COVID-19-associated multisystem inflammatory syndrome in children: Experiences of three centres in Turkey

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dc.creator AKÇAM, Mustafa
dc.creator SALMAN, Hakan
dc.creator Aslan, Nagehan
dc.creator ARSLAN, Müjgan
dc.creator Akkuzu, Emine
dc.creator YILMAZ KESKİN, Ebru
dc.creator Acari, Ceyhun
dc.creator KESKİN, Mahmut
dc.creator ATAR, Müge
dc.creator Kosker, Muhammet
dc.creator Sinanoglu, Selcuk
dc.creator ÇETİN, Hasan
dc.creator AKÇAM, Füsun Zeynep
dc.date 2022-02-01T00:00:00Z
dc.date.accessioned 2022-05-10T11:28:56Z
dc.date.available 2022-05-10T11:28:56Z
dc.identifier c0a64a26-8f12-4b78-a579-04e748a31264
dc.identifier 10.1093/mr/roab042
dc.identifier https://avesis.sdu.edu.tr/publication/details/c0a64a26-8f12-4b78-a579-04e748a31264/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96913
dc.description Background The pathogenesis and clinical manifestations of the multisystem inflammatory syndrome in children (MIS-C) has not yet been fully elucidated and there is no clear consensus on its treatment yet. Objectives To evaluate our patients diagnosed with MIS-C and present them to the literature in order to contribute to the better understanding of this new disease, which entered paediatric practice with the SARS-CoV-2 peak. Methods In this study, 17 MIS-C cases diagnosed according to the Centers for Disease Control and Prevention criteria were included. Results Of the patients, 7 (41.2%) had a comorbidity. Gastrointestinal system involvement was the most prominent in the patients (70.6%). Laparotomy was performed in 3 patients due to acute abdomen. Two patients had neurological involvement. Of the patients, 15 (88.2%) received intravenous immunoglobulin and 13 (76.5%) received both intravenous immunoglobulin and methylprednisolone. Two patients received invasive mechanical ventilation and 4 patients received high flow rate nasal cannula oxygen therapy. One of our patients who needed invasive mechanical ventilation and high vasoactive-inotrope support died despite all supportive treatments including plasmapheresis and extracorporeal membrane oxygenation. Conclusions MIS-C picture can have a fatal course and may present with severe gastrointestinal and neurological signs. Unnecessary laparotomy should be avoided.
dc.language eng
dc.rights info:eu-repo/semantics/openAccess
dc.title COVID-19-associated multisystem inflammatory syndrome in children: Experiences of three centres in Turkey
dc.type info:eu-repo/semantics/article


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