| dc.creator |
Hatamkhani, Shima |
|
| dc.creator |
Tekin, Burcu |
|
| dc.creator |
Heidari, Nadia |
|
| dc.creator |
Kirboga, Kevser Kuebra |
|
| dc.creator |
Akca, Ilknur |
|
| dc.creator |
Naderi, Roya |
|
| dc.creator |
Farnamian, Yeghaneh |
|
| dc.creator |
Alipour, Shahryar |
|
| dc.creator |
Rasmi, Yousef |
|
| dc.date |
2022-06-01T00:00:00Z |
|
| dc.date.accessioned |
2023-01-09T12:01:17Z |
|
| dc.date.available |
2023-01-09T12:01:17Z |
|
| dc.identifier |
31b0866d-b7a4-4429-b7fc-dd86e38b3dfa |
|
| dc.identifier |
10.1016/j.clinbiochem.2022.03.002 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/31b0866d-b7a4-4429-b7fc-dd86e38b3dfa/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/97719 |
|
| dc.description |
Coronavirus Disease 2019 [COVID-19], caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV2], has rapidly evolved into a global health emergency. Neopterin [NPT], produced by macrophages when stimulated with interferon [IFN-]gamma, is an essential cytokine in the antiviral immune response. NPT has been used as a marker for the early assessment of disease severity in different diseases. The leading cause of NPT production is the pro-inflammatory cytokine IFN-. Macrophage activation has also been revealed to be linked with disease severity in SARS-CoV-2 patients. We demonstrate the importance of NPT in the pathogenesis of SARS-CoV-2 and suggest that targeting NPT in SARS-CoV-2 infection may be critical in the early prediction of disease progression and provision of timely management of infected individuals. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
The importance of neopterin in COVID-19: The prognostic value and relation with the disease severity |
|
| dc.type |
info:eu-repo/semantics/article |
|