| dc.creator |
Kortholt, Arjan |
|
| dc.creator |
van Haastert, Peter J. M. |
|
| dc.date |
2008-08-01T00:00:00Z |
|
| dc.date.accessioned |
2023-01-09T12:04:52Z |
|
| dc.date.available |
2023-01-09T12:04:52Z |
|
| dc.identifier |
834eb821-8eb6-4d16-9943-55c4bf3db0bf |
|
| dc.identifier |
10.1016/j.cellsig.2008.02.006 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/834eb821-8eb6-4d16-9943-55c4bf3db0bf/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98071 |
|
| dc.description |
Chemotaxis, the directional movement towards a chemical compound, is an essential property of many cells and has been linked to the development and progression of many diseases. Eukaryotic chemotaxis is a complex process involving gradient sensing, cell polarity, remodelling of the cytoskeleton and signal relay. Recent studies in the model organism Dictyostelium discoideum have shown that chemotaxis does not depend on a single molecular mechanism, but rather depends on several interconnecting pathways. Surprisingly, small G-proteins appear to play essential roles in all these pathways. This review will summarize the role of small G-proteins in Dictyostelium, particularly highlighting the function of the Ras subfamily in chemotaxis. (c) 2008 Elsevier Inc. All rights reserved. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/openAccess |
|
| dc.title |
Highlighting the role of Ras and Rap during Dictyostelium chemotaxis |
|
| dc.type |
info:eu-repo/semantics/article |
|