| dc.creator |
IBRAHIM, Bashar |
|
| dc.creator |
Ozturk, Ali |
|
| dc.creator |
Bayraktar, Nihayet |
|
| dc.creator |
Bayraktar, Mustafa |
|
| dc.creator |
Bozok, Taylan |
|
| dc.creator |
Ceylan, Mehmet Resat |
|
| dc.date |
2022-01-01T00:00:00Z |
|
| dc.date.accessioned |
2023-01-09T12:07:15Z |
|
| dc.date.available |
2023-01-09T12:07:15Z |
|
| dc.identifier |
b86ccfae-949c-40b2-8f75-905557b91ccd |
|
| dc.identifier |
10.5937/jomb0-37514 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/b86ccfae-949c-40b2-8f75-905557b91ccd/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98292 |
|
| dc.description |
© 2022 Sciendo. All rights reserved.Background: Amino acids have an important role in metabolism and may affect COVID-19-related outcomes. In our study, the amino acid serum level of hospitalized COVID-19 patients was evaluated to determine a new treatment strategy. Methods: The amino acid profile covering 43 amino acids in 68 subjects, comprising 30 (14 men and 16 women) controls and 38 (16 men and 22 women) COVID-19 patients, were examined. The amino acid profiles of the participants were screened by LC-MS/MS. Results: Compared with the control group, serum levels of 27 amino acids increased in the patient group. Alpha-aminopimelic acid, sarcosine, and hydroxyproline amino acids were considerably higher in the control group than in the patient group (p<0.0001). There was no notable difference among control group and the case group for 13 amino acids (p≥0.05). A significant positive correlation was seen among the control and the patient groups in the mean amino acid values (r=0.937; p<0.0001). Conclusions: These results postulated a clear picture on the serum levels of amino acid in the COVID-19 patients. Serum amino acids measured in hospitalized COVID-19 patients can explain the patient’s metabolic status during the disease. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/openAccess |
|
| dc.title |
EVALUATION OF AMINO ACID PROFILE IN SERUM OF PATIENTS WITH COVID-19 FOR PROVIDING A NEW TREATMENT STRATEGY PROCENA AMINOKISELINSKOG PROFILA U SERUMU PACIJENATA SA COVID-19 ZA OBEZBE\IVANJE NOVE STRATEGIJE LE^ENJA |
|
| dc.type |
info:eu-repo/semantics/article |
|