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A Randomized Controlled Trial Comparing Two Different Local Intraurethral Anesthetics in Optical Internal Urethrotomy at the Outpatient Clinic

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dc.creator AYDEMİR, Sabri
dc.creator ÖZTÜRK, Sefa Alperen
dc.creator ERGÜN, Osman
dc.date 2022-01-01T00:00:00Z
dc.date.accessioned 2023-01-09T12:07:59Z
dc.date.available 2023-01-09T12:07:59Z
dc.identifier c95dd467-c8d0-47ba-b54a-f63ceeea32bf
dc.identifier 10.1016/j.urology.2022.08.033
dc.identifier https://avesis.sdu.edu.tr/publication/details/c95dd467-c8d0-47ba-b54a-f63ceeea32bf/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98359
dc.description © 2022 Elsevier Inc.Objective: To assess feasibility and efficacy of local topical urethral anesthesia at optical internal urethrotomy (OIU) in patients with anterior and posterior urethral strictures at outpatient clinic. Methods: One hundred and twenty eight patients were prospectively randomized to perform OIU with intraurethral prilocaine solution (group 1 = 64 patients) or intraurethral lidocaine gel (group 2 = 64 patients). Visual analog scale was used for procedure related pain evaluation at the beginning, during, and one hour after the procedure. All patients had follow-ups for a minimum of 12 months. Treatment failure was defined as Qmax < 12ml/sec at uroflowmetry and observed urethral stricture on cystoscopy. Results: The overall success rate of the OIU was 75.8%. The intraoperative mean visual analogue score in group 2 (5,1 ± 1,77) was significantly higher than the group 1 (3.7 ± 1.9) (P = 0.0001). The median time to stricture recurrence was 9.2 months (range 1-13 months). Stricture recurrences were noted in 15 patients in Group 1 and 16 patients in Group 2 during the follow-up period. Conclusion: Prilocaine solution as a local anesthetic is a better option than intraurethral lidocaine gel in the OIU procedure and allows successful OIU to be performed in outpatient clinic. It can be preferred as a local anesthetic for OIU, particularly in unfit patients for general/regional anesthesia. Although it provides successful pain relief, it still cannot prevent experiencing moderate or severe pain in a group of patients. More studies about more effective local anesthetics for pain relief during OIU at the outpatient clinic are required.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title A Randomized Controlled Trial Comparing Two Different Local Intraurethral Anesthetics in Optical Internal Urethrotomy at the Outpatient Clinic
dc.type info:eu-repo/semantics/article


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