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BENZOIC ACID DERIVATIVES: ANTI-BIOFILM ACTIVITY IN PSEUDOMONAS AERUGINOSA PAO1, QUANTUM CHEMICAL CALCULATIONS BY DFT AND MOLECULAR DOCKING STUDY br

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dc.creator ÖNEM, Ebru
dc.creator OTURAK, Halil
dc.creator Kinayturk, Neslihan Kaya
dc.date 2023-01-01T00:00:00Z
dc.date.accessioned 2023-01-09T12:09:17Z
dc.date.available 2023-01-09T12:09:17Z
dc.identifier e6cb6f43-0256-4621-9287-71bfa213732d
dc.identifier 10.4314/bcse.v37i1.14
dc.identifier https://avesis.sdu.edu.tr/publication/details/e6cb6f43-0256-4621-9287-71bfa213732d/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98485
dc.description Quorum sensing (QS), used by many pathogenic bacteria to express virulence factors, is seen as a new and effective strategy to combat resistant bacteria. In this study, theoretical investigations were made on the structural data of molecules to support the inhibition effects of 2-amino 4-chloro benzoic acid and 4-amino 2-chloro benzoic acid molecules. Theoretical calculations were performed by using the density functional theory with the B3LYP function and aug-cc-pVDZ basis set in the gas phase of the isolated compounds in the ground state. The biological activities of the related compounds were theoretically investigated against Covid-19 protein (PDB ID: 6LU7).
dc.language eng
dc.rights info:eu-repo/semantics/openAccess
dc.title BENZOIC ACID DERIVATIVES: ANTI-BIOFILM ACTIVITY IN PSEUDOMONAS AERUGINOSA PAO1, QUANTUM CHEMICAL CALCULATIONS BY DFT AND MOLECULAR DOCKING STUDY br
dc.type info:eu-repo/semantics/article


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