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Melatonin receptor agonist ramelteon alleviates experimental acute ocular inflammation via HIF-1 Alpha/VEGF/E-NOS signaling

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dc.creator SAVRAN, Mehtap
dc.creator ERZURUMLU, Yalçın
dc.creator USTA SOFU, Gülşah
dc.creator KARACA, Umut
dc.creator CANDAN, İBRAHİM AYDIN
dc.creator Hasseyid, Nursel
dc.creator AŞCI, Halil
dc.date 2023-03-01T00:00:00Z
dc.identifier ecbc888f-b205-47f1-84e2-1528473583a1
dc.identifier 10.1177/11206721221123878
dc.identifier https://avesis.sdu.edu.tr/publication/details/ecbc888f-b205-47f1-84e2-1528473583a1/oai
dc.description Purpose: Ramelteon (RML) is a potent, selective agonist of the high-affinity melatonin receptor 1 and 2 receptors. In addition, RML is known to have antioxidant and anti-inflammatory effects. In this study, we aimed to investigate the effects of RML on HIF-1 alpha, VEGF and e-NOS signaling pathway in a rat model of endotoxin-induced uveitis (EIU).
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Melatonin receptor agonist ramelteon alleviates experimental acute ocular inflammation via HIF-1 Alpha/VEGF/E-NOS signaling
dc.type info:eu-repo/semantics/article


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