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A comparative study on biological activities of different solvent extracts from whole seed, seed coat and cotyledon of two Lathyrus species

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dc.creator Yildirim, Bekir
dc.creator Genc, Hasan
dc.creator Yazici, Sercan Ozbek
dc.creator ÖZMEN, İsmail
dc.date 2022-01-01T00:00:00Z
dc.date.accessioned 2023-01-09T12:10:12Z
dc.date.available 2023-01-09T12:10:12Z
dc.identifier fa6fbda9-fdea-4966-b333-ff18fb3d52b3
dc.identifier 10.1590/s2175-97902022e20255
dc.identifier https://avesis.sdu.edu.tr/publication/details/fa6fbda9-fdea-4966-b333-ff18fb3d52b3/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98566
dc.description © 2022, Faculdade de Ciencias Farmaceuticas (Biblioteca). All rights reserved.The present study was conducted to assess the phenolic content, and antibacterial and antioxidant activities of Lathyrus L. species. The extraction of phenolic compounds from whole seeds, seed coat and cotyledon of Lathyrus hierosolymitanus Boiss. and Lathyrus annuus L. seeds was performed employing different solvents. Total phenolic content (TPC) was measured by Folin-Ciocalteau assay, while the antioxidant activity was determined by DPPH radical scavenging activity, and reducing power assay. It was found that TPC of extracts ranged from 0.12 mg to 6.53 mg GAE/gdw. For each solvent, seed coat extracts were generally observed to render higher TPC and antioxidant activities. There was a correlation between TPC and antioxidant activity. In addition, all extracts were also examined for their antimicrobial activity against Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa. Methanol extracts showed the highest antibacterial activity which is consistent with TPC, but there was no correlation between TPC and antibacterial activity. Solvents were observed to have effects on gallic acid, caffeic acid, and epicatechin extractions. HPLC analysis results of extracts confirmed methanol and ethanol as preferred solvents for phenolic extraction from Lathyrus sp. Phenolic content in the extracts could be suggested to contribute to their antioxidant and antibacterial activity.
dc.language eng
dc.rights info:eu-repo/semantics/openAccess
dc.title A comparative study on biological activities of different solvent extracts from whole seed, seed coat and cotyledon of two Lathyrus species
dc.type info:eu-repo/semantics/article


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