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A rare case report: testicular leydig cell tumor with gynecomastia

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dc.creator Özorak, Alper
dc.creator Çifteci, Tayfun
dc.creator Öztürk, Sefa Alperen
dc.date 2022-08-01T00:00:00Z
dc.date.accessioned 2024-08-26T12:05:10Z
dc.date.available 2024-08-26T12:05:10Z
dc.identifier 0548fb07-2e82-4ceb-9ac1-e56a7f13354f
dc.identifier 10.56150/tjhsl.905679
dc.identifier https://avesis.sdu.edu.tr/publication/details/0548fb07-2e82-4ceb-9ac1-e56a7f13354f/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98636
dc.description <p>Gynecomastia is the most common definition of breast tissue growth. It is common in urology due to androgen blockage used in prostate cancers. Clinicallyinsignificant gynecomastia is present in 50% of men and there is no proliferationof breast tissue in ductus epithelium. Gynecomastia is rarely seen in primary testicular tumors such as Leydig Cell Tumors (LCT). Leydig Cell Tumors are one ofthe rare sex cord stromal cell tumors of the testis. Although it is usually with endocrine changes, it is a painless mass or incidentally occurring tumor in the testis.In this case report, we examined a 43-year-old left testicular Leydig cell tumorfollowed up with gynecomastia. He had been admitted to our clinic for gynecomastia and breast pain for 6 years. The patient was followed-up by endocrinology due to the aforementioned complaints. Pituitary MRI was performed with thesuspicion of prolactinoma, but no pathology was found. Since the physical examination was unremarkable, MRI of the lower abdomen was requested from thepatient. MRI reported as 20*20 mm in size (testicular tumor?) in the left intratesticular area. The patient underwent left inguinal orchiectomy and the pathology report was positive for the leydig cell tumor. 30% of patients with Leydigcell tumors present with gynecomastia. Ultrasonography is accepted as the firstresearch method for the diagnosis of leydic cell tumor, but MRI is superior toultrasonography in diagnosis. The gold standard treatment option is radical inguinal orchiectomy. The mechanism of hormonal disorders may be an overproduction of testosterone and estrogens by the tumor. As in our case, it is necessary toconsider the possibility of LCT which is rarely seen in patients with gynecomastiaand to provide differential diagnosis by performing the tests in this direction.&nbsp;<br></p>
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title A rare case report: testicular leydig cell tumor with gynecomastia
dc.type info:eu-repo/semantics/article


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