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SYNTHESIS AND ANTICANCER ACTIVITY OF 5- CHLORO-3-((6-CHLORO- [1,2,4]TRIAZOLO[4,3- b]PYRIDAZIN-3-YL)METHYL)BENZO[d]THIAZOL- 2(3H)- ONE

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dc.creator Özçelik, Azime Berna
dc.creator Oruç, Hatice
dc.creator Akdağ, Mevlüt
dc.creator Arslan, Gülnur
dc.date 2023-05-06T00:00:00Z
dc.date.accessioned 2024-08-26T12:08:03Z
dc.date.available 2024-08-26T12:08:03Z
dc.identifier 0d606dce-4f66-4e85-b00c-e3bd47cc0080
dc.identifier https://avesis.sdu.edu.tr/publication/details/0d606dce-4f66-4e85-b00c-e3bd47cc0080/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98719
dc.description <p>Breast cancer is the most common cause of cancer cases among women worldwide estimated to cause 1 million deaths in 2040 [1]. Heterocycles are important building blocks of anticancer agents [2]. Of the aromatic heterocycle compounds, it has been widely reported that nitrogenbased heterocycles and benzothiazole derivatives have anticancer properties [2-4]. In this study, benzothiazol-2(3H)-one and [1,2,4]triazolo[4,3-b]pyridazine cores were merged and 5-chloro-3-((6-chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)benzo[d]thiazol-2(3H)-one compound was designed. The compound was synthesized by both conventional and microwave irradiation methods. It was evaluated against MCF-7 breast cancer cells<br></p>
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title SYNTHESIS AND ANTICANCER ACTIVITY OF 5- CHLORO-3-((6-CHLORO- [1,2,4]TRIAZOLO[4,3- b]PYRIDAZIN-3-YL)METHYL)BENZO[d]THIAZOL- 2(3H)- ONE
dc.type info:eu-repo/semantics/conferenceObject


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