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Mortality in psoriatic arthritis patients, changes over time, and the impact of COVID-19: results from a multicenter Psoriatic Arthritis Registry (PsART-ID)

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dc.creator Akar, Servet
dc.creator Yazısız, Veli
dc.creator Kasifoglu, Timucin
dc.creator Yilmaz, Sema
dc.creator Özisler, Cem
dc.creator AYAN, GİZEM
dc.creator Ersozlu, Emine Duygu
dc.creator Bayindir, Ozun
dc.creator KILIÇ, LEVENT
dc.creator DALKILIÇ, HÜSEYİN EDİZ
dc.creator Esmen, Serpil Ergulu
dc.creator DOĞRU, Atalay
dc.creator Omma, Ahmet
dc.creator Duruoz, Tuncay
dc.creator Küçüksahin, Orhan
dc.creator Yildiz, Fatih
dc.creator Kimyon, Gezmis
dc.creator Erden, Abdulsamet
dc.creator Aydin, Sibel Zehra
dc.creator Tarhan, Emine Figen
dc.creator Bakirci, Sibel
dc.creator Günal, Esen Kasapoglu
dc.creator Cetin, Gözde Yildirim
dc.creator Gonullu, Emel
dc.creator Aksu, Kenan
dc.creator Tufan, Abdurrahman
dc.creator Pehlevan, Seval
dc.creator Solmaz, Dilek
dc.creator Cinar, Muhammed
dc.creator Kalyoncu, Umut
dc.date 2023-02-01T00:00:00Z
dc.date.accessioned 2024-08-26T12:08:18Z
dc.date.available 2024-08-26T12:08:18Z
dc.identifier 10dd9cec-9e2d-4995-9582-955ae30f3e8d
dc.identifier 10.1007/s10067-022-06492-6
dc.identifier https://avesis.sdu.edu.tr/publication/details/10dd9cec-9e2d-4995-9582-955ae30f3e8d/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98747
dc.description © 2023, The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR).Background: This study aimed to assess the mortality of PsA before and during the COVID-19 pandemic. Methods: From the prospective, multicenter PsART-ID (Psoriatic Arthritis Registry-International Database), patients from Turkey were analyzed by linking the registry to the Turkish Cause of Death Registry. The outcome of interest was death from any cause, pre-pandemic (since the onset of registry—March 2014–March 2020), and during the pandemic (March 2020–May 2021). The crude mortality rate and standardized mortality ratio (SMR) were determined. Results: There were 1216 PsA patients with a follow-up of 7500 patient-years. Overall, 46 deaths (26 males) were observed. In the pre-pandemic period, SMR for PsA vs the general population was 0.95 (0.61–1.49), being higher in males [1.56 (0.92–2.63)] than females [0.62 (0.33–1.17)]. The crude mortality rate in PsA doubled during the pandemic (pre-pandemic crude mortality rate: 5.07 vs 10.76 during the pandemic) with a higher increase in females (2.9 vs 8.72) than males (9.07 vs 14.73). Conclusion: The mortality in PsA was found similar to the general population in the pre-pandemic era. The mortality rates in PsA doubled during the pandemic. Whether PsA patients have more risk of mortality than the general population due to COVID-19 needs further studies.Key Points• Decrease in mortality in PsA might be expected with the more effective treatment options and better disease control.• A crude mortality rate is comparable to the general population and not increased until the pandemic.• Currently, there is a 2-fold increase in crude mortality rate possibly due to the COVID-19.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Mortality in psoriatic arthritis patients, changes over time, and the impact of COVID-19: results from a multicenter Psoriatic Arthritis Registry (PsART-ID)
dc.type info:eu-repo/semantics/article


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