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Analysis of Serum VEGF, IGF-1, and HIF-1α Levels in ADHD

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dc.creator Işık, Ümit
dc.creator ŞİRİN, Fevziye Burcu
dc.creator ERTÜRK, Emre
dc.date 2024-01-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:18:31Z
dc.date.available 2025-02-25T10:18:31Z
dc.identifier 233f0bca-e21c-4471-b17a-04495325d305
dc.identifier 10.1177/10870547231197211
dc.identifier https://avesis.sdu.edu.tr/publication/details/233f0bca-e21c-4471-b17a-04495325d305/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/99064
dc.description Objective: In recent years, it has been emphasized that various growth factors that affect neurogenesis may lead to ADHD. In this study, we aimed to investigate the role of VEGF, IGF-1, and HIF-1α growth factors in the etiopathogenesis of ADHD. Method: Levels of VEGF, IGF-1, and HIF-1α were compared between 40 ADHD children and 40 healthy children, aged 7 to 13 years. Result: VEGF, IGF-1, and HIF-1α levels did not significantly differ between the groups. There was a negative correlation between serum VEGF levels and the parent-rated T-DSM-IV-S (AD) subscale. There was a positive correlation between serum IGF-1 levels and the parent-rated T-DSM-IV-S (AD) subscale, and SDQ (ES) subscale. Conclusion: Given our limitations and the fact that some of our findings differ from those of other studies, it is evident that this area requires additional research with larger samples.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Analysis of Serum VEGF, IGF-1, and HIF-1α Levels in ADHD
dc.type info:eu-repo/semantics/article


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